Heparin-induced thrombocytopenia following pancreatectomy and islet auto-transplantation

Cristiana Rastellini, Melissa L. Brown, Luca Cicalese

Research output: Contribution to journalArticle

Abstract

We report the case of a female with chronic pancreatitis who underwent multiple surgical procedures leading to total resection of the pancreas with successful islet auto-transplantation. Postoperatively, she developed heparin-induced thrombocytopenia. Heparinization prior to islet infusion is currently recommended to prevent portal vein thrombosis. Antibodies against heparin are not standard pre-operative testing for islet transplantation. Timely screening for heparin-dependent anti-platelet antibody should be kept in consideration for elective surgical cases (especially following previous surgeries) including pancreatic islet allo- and auto-transplantation.

Original languageEnglish (US)
Pages (from-to)156-158
Number of pages3
JournalClinical Transplantation
Volume20
Issue number2
DOIs
StatePublished - Mar 2006
Externally publishedYes

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Keywords

  • Heparin-induced thrombocytopenia
  • Islet transplant
  • Pancreatectomy

ASJC Scopus subject areas

  • Transplantation
  • Immunology

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