Heparin-induced thrombocytopenia following pancreatectomy and islet auto-transplantation

Cristiana Rastellini, Melissa L. Brown, Luca Cicalese

Research output: Contribution to journalArticle

Abstract

We report the case of a female with chronic pancreatitis who underwent multiple surgical procedures leading to total resection of the pancreas with successful islet auto-transplantation. Postoperatively, she developed heparin-induced thrombocytopenia. Heparinization prior to islet infusion is currently recommended to prevent portal vein thrombosis. Antibodies against heparin are not standard pre-operative testing for islet transplantation. Timely screening for heparin-dependent anti-platelet antibody should be kept in consideration for elective surgical cases (especially following previous surgeries) including pancreatic islet allo- and auto-transplantation.

Original languageEnglish (US)
Pages (from-to)156-158
Number of pages3
JournalClinical Transplantation
Volume20
Issue number2
DOIs
StatePublished - Mar 2006
Externally publishedYes

Fingerprint

Islets of Langerhans Transplantation
Pancreatectomy
Thrombocytopenia
Heparin
Chronic Pancreatitis
Portal Vein
Pancreas
Anti-Idiotypic Antibodies
Thrombosis
Blood Platelets
Transplantation
Antibodies

Keywords

  • Heparin-induced thrombocytopenia
  • Islet transplant
  • Pancreatectomy

ASJC Scopus subject areas

  • Transplantation
  • Immunology

Cite this

Heparin-induced thrombocytopenia following pancreatectomy and islet auto-transplantation. / Rastellini, Cristiana; Brown, Melissa L.; Cicalese, Luca.

In: Clinical Transplantation, Vol. 20, No. 2, 03.2006, p. 156-158.

Research output: Contribution to journalArticle

Rastellini, Cristiana ; Brown, Melissa L. ; Cicalese, Luca. / Heparin-induced thrombocytopenia following pancreatectomy and islet auto-transplantation. In: Clinical Transplantation. 2006 ; Vol. 20, No. 2. pp. 156-158.
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