Heparin-induced thrombocytopenia following pancreatectomy and islet auto-transplantation

Cristiana Rastellini; Melissa L. Brown; Luca Cicalese

doi:10.1111/j.1399-0012.2005.00457.x

Heparin-induced thrombocytopenia following pancreatectomy and islet auto-transplantation

Cristiana Rastellini, Melissa L. Brown, Luca Cicalese

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

We report the case of a female with chronic pancreatitis who underwent multiple surgical procedures leading to total resection of the pancreas with successful islet auto-transplantation. Postoperatively, she developed heparin-induced thrombocytopenia. Heparinization prior to islet infusion is currently recommended to prevent portal vein thrombosis. Antibodies against heparin are not standard pre-operative testing for islet transplantation. Timely screening for heparin-dependent anti-platelet antibody should be kept in consideration for elective surgical cases (especially following previous surgeries) including pancreatic islet allo- and auto-transplantation.

Original language	English (US)
Pages (from-to)	156-158
Number of pages	3
Journal	Clinical Transplantation
Volume	20
Issue number	2
DOIs	https://doi.org/10.1111/j.1399-0012.2005.00457.x
State	Published - Mar 2006
Externally published	Yes

Keywords

Heparin-induced thrombocytopenia
Islet transplant
Pancreatectomy

ASJC Scopus subject areas

Transplantation

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10.1111/j.1399-0012.2005.00457.x

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title = "Heparin-induced thrombocytopenia following pancreatectomy and islet auto-transplantation",

abstract = "We report the case of a female with chronic pancreatitis who underwent multiple surgical procedures leading to total resection of the pancreas with successful islet auto-transplantation. Postoperatively, she developed heparin-induced thrombocytopenia. Heparinization prior to islet infusion is currently recommended to prevent portal vein thrombosis. Antibodies against heparin are not standard pre-operative testing for islet transplantation. Timely screening for heparin-dependent anti-platelet antibody should be kept in consideration for elective surgical cases (especially following previous surgeries) including pancreatic islet allo- and auto-transplantation.",

keywords = "Heparin-induced thrombocytopenia, Islet transplant, Pancreatectomy",

author = "Cristiana Rastellini and Brown, {Melissa L.} and Luca Cicalese",

year = "2006",

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AU - Brown, Melissa L.

AU - Cicalese, Luca

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Y1 - 2006/3

N2 - We report the case of a female with chronic pancreatitis who underwent multiple surgical procedures leading to total resection of the pancreas with successful islet auto-transplantation. Postoperatively, she developed heparin-induced thrombocytopenia. Heparinization prior to islet infusion is currently recommended to prevent portal vein thrombosis. Antibodies against heparin are not standard pre-operative testing for islet transplantation. Timely screening for heparin-dependent anti-platelet antibody should be kept in consideration for elective surgical cases (especially following previous surgeries) including pancreatic islet allo- and auto-transplantation.

AB - We report the case of a female with chronic pancreatitis who underwent multiple surgical procedures leading to total resection of the pancreas with successful islet auto-transplantation. Postoperatively, she developed heparin-induced thrombocytopenia. Heparinization prior to islet infusion is currently recommended to prevent portal vein thrombosis. Antibodies against heparin are not standard pre-operative testing for islet transplantation. Timely screening for heparin-dependent anti-platelet antibody should be kept in consideration for elective surgical cases (especially following previous surgeries) including pancreatic islet allo- and auto-transplantation.

KW - Heparin-induced thrombocytopenia

KW - Islet transplant

KW - Pancreatectomy

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Heparin-induced thrombocytopenia following pancreatectomy and islet auto-transplantation

Abstract

Keywords

ASJC Scopus subject areas

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