Hepatitis E presenting with thrombocytopaenia

Irfan Masood, Ali Rafiq, Zain Majid

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


We hereby present the case of a 25-year-old man who presented at the emergency department of Civil Hospital Karachi, Pakistan with signs and symptoms of acute viral hepatitis. Serology tests revealed that the patient was suffering from hepatitis E viral (HEV) infection. Concurrently, the patient was also found to have thrombocytopaenia (TCP). His TCP became better after the resolution of his jaundice, with the patient requiring a transfusion of one mega unit of platelets. After ruling out other common causes of TCP and after a thorough literature search, we concluded that an immune-mediated mechanism secondary to HEV infection might have been the cause behind his low platelet counts. Hence, we propose considering the possibility of HEV infection in patients presenting with acute liver failure and TCP, irrespective of age, gender, and geographical location of the patient.

Original languageEnglish (US)
Pages (from-to)219-220
Number of pages2
JournalTropical Doctor
Issue number4
StatePublished - Oct 2014
Externally publishedYes


  • Hepatitis E
  • immune-mediated
  • thrombocytopaenia
  • young male

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases


Dive into the research topics of 'Hepatitis E presenting with thrombocytopaenia'. Together they form a unique fingerprint.

Cite this