Hexosaminidase

A biochemical marker for necrotizlng enterocolitls in the preterm infant

Thom E. Lobe, Carol Richardson, David K. Rassin, Ross Mills, Marshall Schwartz

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

To evaluate hexosaminidase as a biochemical marker for the early detection of necrotizing enterocolitis in preterm infants, 33 preterm infants without necrotizing enterocolitis and 18 preterm infants with necrotizing enterocolitis had hexosaminidase activity measured during the course of their hospitalization. Although hexosaminidase activity could not identify those preterm infants with necrotizing enterocolitis who had impending perforation, the data strongly suggest that measurements of serum hexosaminidase activity may provide an early biochemical indication of the presence of necrotizing enterocolitis in the preterm infant. Hopefully, early detection of necrotizing enterocolitis in these infants will reduce the morbidity and mortality of this disease.

Original languageEnglish (US)
Pages (from-to)49-52
Number of pages4
JournalThe American Journal of Surgery
Volume147
Issue number1
DOIs
StatePublished - 1984
Externally publishedYes

Fingerprint

Hexosaminidase A
Necrotizing Enterocolitis
Premature Infants
Hexosaminidases
Biomarkers
Hospitalization
Morbidity
Mortality
Serum

ASJC Scopus subject areas

  • Surgery

Cite this

Hexosaminidase : A biochemical marker for necrotizlng enterocolitls in the preterm infant. / Lobe, Thom E.; Richardson, Carol; Rassin, David K.; Mills, Ross; Schwartz, Marshall.

In: The American Journal of Surgery, Vol. 147, No. 1, 1984, p. 49-52.

Research output: Contribution to journalArticle

Lobe, Thom E. ; Richardson, Carol ; Rassin, David K. ; Mills, Ross ; Schwartz, Marshall. / Hexosaminidase : A biochemical marker for necrotizlng enterocolitls in the preterm infant. In: The American Journal of Surgery. 1984 ; Vol. 147, No. 1. pp. 49-52.
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