High-mobility group box 1 inhibits HCO₃^_ absorption in the medullary thick ascending limb through RAGE-rho-ROCK-mediated inhibition of basolateral Na⁺/H⁺ exchange

Keyphrases

• Medullary Thick Ascending Limb 100%
• H+ Exchange 100%
• HCO3 100%
• Na + 100%
• Receptor for Advanced Glycation End Products 100%
• High Mobility Group Box 1 (HMGB1) 100%
• Rho Kinase 100%
• RhoA 25%
• Signaling Mechanism 16%
• Transport Mechanism 16%
• Sepsis 16%
• Inflammatory Disorders 16%
• NHE1 16%
• Rho Kinase Inhibitor 16%
• Immune Response 8%
• Specific Inhibitor 8%
• Signaling Pathway 8%
• Receptor Signaling 8%
• Toll-like 8%
• Nuclear Proteins 8%
• Response to Infection 8%
• Response to Injury 8%
• Filamentous Actin (F-actin) 8%
• Or Injury 8%
• Stabilizer 8%
• Kidney Disease 8%
• Amiloride 8%
• A1 Receptor 8%
• Limb Function 8%
• Y-27632 8%
• Jasplakinolide 8%
• FPS-ZM1 8%
• Limb Dysfunction 8%

Medicine and Dentistry

• Limb 100%
• Sodium Ion 100%
• Advanced Glycation End Product Receptor 100%
• Rho Kinase 100%
• Sepsis 33%
• Inflammatory Disorder 33%
• Phosphotransferase Inhibitor 33%
• Injury 16%
• Infection 16%
• Immune Response 16%
• Nuclear Protein 16%
• Mediator 16%
• Receptor 16%
• Signal Transduction 16%
• Actin 16%
• Toll Like Receptor 4 16%
• Amiloride 16%
• Kidney Dysfunction 16%
• Y-27632 16%
• Jaspamide 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Sodium Ion 100%
• Advanced Glycation End Product Receptor 100%
• Rho Kinase 100%
• Disease 40%
• Sepsis 40%
• Phosphotransferase Inhibitor 40%
• Injury 20%
• Infection 20%
• Toll Like Receptor 4 20%
• Receptor 20%
• Nuclear Protein 20%
• Actin 20%
• Amiloride 20%
• Kidney Dysfunction 20%
• Jaspamide 20%
• 4 (1 Aminoethyl) N (4 Pyridyl)cyclohexanecarboxamide 20%