High-throughput measurement of the Tp53 response to anticancer drugs and random compounds using a stably integrated

Pharmacology, Toxicology and Pharmaceutical Science

• Anticarcinogen 100%
• Environmental Exposure 66%
• Dabequine 66%
• Antimalarial Agent 66%
• Malignant Neoplasm 33%
• Colorectal Carcinoma 33%
• Protein P53 33%
• Chloroquine 33%
• Mutagenicity 33%
• Biological Product 33%
• Ionizing Radiation 33%
• Genotoxicity 33%
• Hydralazine 33%
• Nifedipine 33%
• DNA Topoisomerase 33%
• Flavonoid 33%
• Amsacrine 33%
• Amodiaquine 33%
• Mepacrine 33%
• Compounds of Lead 33%
• Antihypertensive Agent 33%
• Cytotoxicity 33%

Keyphrases

• Tumor Protein p53 (TP53) 100%
• Anticancer Drugs 100%
• High-throughput Measurement 100%
• Inducer 12%
• Environmental Exposure 12%
• Cells in Culture 6%
• Colorectal Cancer 6%
• Cancer Cells 6%
• Reporter System 6%
• P53 Protein 6%
• Cytotoxicity 6%
• Null Cell 6%
• Chloroquine 6%
• Ionizing Radiation 6%
• Mutagenicity 6%
• Cellular Stress 6%
• Quinoline 6%
• Biological Properties 6%
• Functional Assay 6%
• Chemical Probes 6%
• Small Molecule Compounds 6%
• Anticancer Agents 6%
• Syngeneic 6%
• P53 Pathway 6%
• Genotoxicity 6%
• Clastogenicity 6%
• Novel Chemotherapeutic Agents 6%
• Hydralazine 6%
• Nifedipine 6%
• Antihypertensive Drugs 6%
• Anticancer Drug Exposure 6%
• N-oxides 6%
• Genetic Status 6%
• Antimalarial Drugs 6%
• Topoisomerase Activity 6%
• Clinical Association 6%
• Amodiaquine 6%
• Quinacrine 6%
• Short-lived Protein 6%
• Flavonoids 6%
• DNA Topoisomerase 6%