Highlights of Cardiovascular Disease Prevention Studies Presented at the 2024 European Society of Cardiology Congress

Vashma Junaid; Abdul Mannan Khan Minhas; Maha Inam; Colin Hinkamp; Khawaja M. Talha; Chelsea Meloche; Sana Sheikh; Adeel Khoja; Chayakrit Krittanawong; Elizabeth M. Vaughan; Dinesh K. Kalra; Leandro Slipczuk; Salim S. Virani

doi:10.1007/s11883-024-01253-z

Highlights of Cardiovascular Disease Prevention Studies Presented at the 2024 European Society of Cardiology Congress

Vashma Junaid, Abdul Mannan Khan Minhas, Maha Inam, Colin Hinkamp, Khawaja M. Talha, Chelsea Meloche, Sana Sheikh, Adeel Khoja, Chayakrit Krittanawong, Elizabeth M. Vaughan, Dinesh K. Kalra, Leandro Slipczuk, Salim S. Virani

Research output: Contribution to journal › Review article › peer-review

Abstract

Purpose of Review: To summarize selected late-breaking science on cardiovascular disease (CVD) prevention presented at the 2024 European Society of Cardiology (ESC) Congress. Recent Findings: Key studies from the 2024 ESC Congress highlight advances in (CVD) management. Apolipoprotein A-1 infusions reduced risk in acute myocardial infarction patients with high LDL cholesterol. Plozasiran cut triglycerides and apolipoprotein C-III levels, lowering pancreatitis risk. A 14-year study linked smoking among youth to cardiac abnormalities. Baseline hsCRP, LDL-C, and Lp(a) were strong predictors of 30-year outcomes in women. Alternative LDL-lowering strategies matched high-intensity statins in effectiveness of LDL-C lowering and reduced diabetes risk. Early combination lipid lowering therapy improved outcomes post-myocardial infarction. Nordic and Mediterranean diets were linked to lower atherosclerotic CVD risk. Summary: The findings from the 2024 ESC Congress highlight significant advancements in CVD prevention, including novel lipid-lowering therapies, biomarker-based risk prediction, and lifestyle interventions. These studies underscore the importance of early and personalized treatment strategies to mitigate long-term cardiovascular risk.

Original language	English (US)
Article number	14
Journal	Current Atherosclerosis Reports
Volume	27
Issue number	1
DOIs	https://doi.org/10.1007/s11883-024-01253-z
State	Published - Dec 2024
Externally published	Yes

Keywords

Apolipoprotein A-1
CACS
CVD Prevention
ESC
LDL-c
Lp(a)
MACE
Plozasiran

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

Access to Document

10.1007/s11883-024-01253-z

Cite this

Junaid, V., Minhas, A. M. K., Inam, M., Hinkamp, C., Talha, K. M., Meloche, C., Sheikh, S., Khoja, A., Krittanawong, C., Vaughan, E. M., Kalra, D. K., Slipczuk, L., & Virani, S. S. (2024). Highlights of Cardiovascular Disease Prevention Studies Presented at the 2024 European Society of Cardiology Congress. Current Atherosclerosis Reports, 27(1), Article 14. https://doi.org/10.1007/s11883-024-01253-z

Junaid, V, Minhas, AMK, Inam, M, Hinkamp, C, Talha, KM, Meloche, C, Sheikh, S, Khoja, A, Krittanawong, C, Vaughan, EM, Kalra, DK, Slipczuk, L & Virani, SS 2024, 'Highlights of Cardiovascular Disease Prevention Studies Presented at the 2024 European Society of Cardiology Congress', Current Atherosclerosis Reports, vol. 27, no. 1, 14. https://doi.org/10.1007/s11883-024-01253-z

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abstract = "Purpose of Review: To summarize selected late-breaking science on cardiovascular disease (CVD) prevention presented at the 2024 European Society of Cardiology (ESC) Congress. Recent Findings: Key studies from the 2024 ESC Congress highlight advances in (CVD) management. Apolipoprotein A-1 infusions reduced risk in acute myocardial infarction patients with high LDL cholesterol. Plozasiran cut triglycerides and apolipoprotein C-III levels, lowering pancreatitis risk. A 14-year study linked smoking among youth to cardiac abnormalities. Baseline hsCRP, LDL-C, and Lp(a) were strong predictors of 30-year outcomes in women. Alternative LDL-lowering strategies matched high-intensity statins in effectiveness of LDL-C lowering and reduced diabetes risk. Early combination lipid lowering therapy improved outcomes post-myocardial infarction. Nordic and Mediterranean diets were linked to lower atherosclerotic CVD risk. Summary: The findings from the 2024 ESC Congress highlight significant advancements in CVD prevention, including novel lipid-lowering therapies, biomarker-based risk prediction, and lifestyle interventions. These studies underscore the importance of early and personalized treatment strategies to mitigate long-term cardiovascular risk.",

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AU - Talha, Khawaja M.

AU - Meloche, Chelsea

AU - Sheikh, Sana

AU - Khoja, Adeel

AU - Krittanawong, Chayakrit

AU - Vaughan, Elizabeth M.

AU - Kalra, Dinesh K.

AU - Slipczuk, Leandro

AU - Virani, Salim S.

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