Highlights on Fluorine-containing Drugs Approved by U.S. FDA in 2023

Saghir Ali, Andrew A. Bolinger, Jia Zhou

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Fluorine continues to show its potential applications in drug discovery and development, as reflected by twelve drugs being fluorinated out of the fifty-five approved by the FDA in 2023. This concise review highlights the discovery of each of these fluorine-containing drugs in the past year, including its brand name, date of approval, composition, sponsors, indication, and mechanism of action. The relevant future trend is also briefly discussed.

Original languageEnglish (US)
Pages (from-to)843-849
Number of pages7
JournalCurrent topics in medicinal chemistry
Issue number10
StatePublished - 2024


  • Diagnostic tools
  • FDA approval
  • Fluorinated drugs
  • Fluorine
  • Small-molecule drug discovery
  • Therapeutics

ASJC Scopus subject areas

  • Drug Discovery


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