Highlights on Fluorine-containing Drugs Approved by U.S. FDA in 2023

Saghir Ali; Andrew A. Bolinger; Jia Zhou

doi:10.2174/0115680266300245240223070242

Highlights on Fluorine-containing Drugs Approved by U.S. FDA in 2023

Saghir Ali, Andrew A. Bolinger, Jia Zhou

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Fluorine continues to show its potential applications in drug discovery and development, as reflected by twelve drugs being fluorinated out of the fifty-five approved by the FDA in 2023. This concise review highlights the discovery of each of these fluorine-containing drugs in the past year, including its brand name, date of approval, composition, sponsors, indication, and mechanism of action. The relevant future trend is also briefly discussed.

Original language	English (US)
Pages (from-to)	843-849
Number of pages	7
Journal	Current topics in medicinal chemistry
Volume	24
Issue number	10
DOIs	https://doi.org/10.2174/0115680266300245240223070242
State	Published - 2024
Externally published	Yes

Keywords

Diagnostic tools
FDA approval
Fluorinated drugs
Fluorine
Small-molecule drug discovery
Therapeutics

ASJC Scopus subject areas

Drug Discovery

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10.2174/0115680266300245240223070242

Cite this

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title = "Highlights on Fluorine-containing Drugs Approved by U.S. FDA in 2023",

abstract = "Fluorine continues to show its potential applications in drug discovery and development, as reflected by twelve drugs being fluorinated out of the fifty-five approved by the FDA in 2023. This concise review highlights the discovery of each of these fluorine-containing drugs in the past year, including its brand name, date of approval, composition, sponsors, indication, and mechanism of action. The relevant future trend is also briefly discussed.",

keywords = "Diagnostic tools, FDA approval, Fluorinated drugs, Fluorine, Small-molecule drug discovery, Therapeutics",

author = "Saghir Ali and Bolinger, {Andrew A.} and Jia Zhou",

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year = "2024",

doi = "10.2174/0115680266300245240223070242",

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AU - Bolinger, Andrew A.

AU - Zhou, Jia

PY - 2024

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N2 - Fluorine continues to show its potential applications in drug discovery and development, as reflected by twelve drugs being fluorinated out of the fifty-five approved by the FDA in 2023. This concise review highlights the discovery of each of these fluorine-containing drugs in the past year, including its brand name, date of approval, composition, sponsors, indication, and mechanism of action. The relevant future trend is also briefly discussed.

AB - Fluorine continues to show its potential applications in drug discovery and development, as reflected by twelve drugs being fluorinated out of the fifty-five approved by the FDA in 2023. This concise review highlights the discovery of each of these fluorine-containing drugs in the past year, including its brand name, date of approval, composition, sponsors, indication, and mechanism of action. The relevant future trend is also briefly discussed.

KW - Diagnostic tools

KW - FDA approval

KW - Fluorinated drugs

KW - Fluorine

KW - Small-molecule drug discovery

KW - Therapeutics

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Highlights on Fluorine-containing Drugs Approved by U.S. FDA in 2023

Abstract

Keywords

ASJC Scopus subject areas

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