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Highly Potent and Selective Dopamine D
4
Receptor Antagonists Potentially Useful for the Treatment of Glioblastoma
Pegi Pavletić
, Ana Semeano
, Hideaki Yano
,
Alessandro Bonifazi
, Gianfabio Giorgioni
, Alessandro Piergentili
, Wilma Quaglia
, Maria Giovanna Sabbieti
, Dimitrios Agas
, Giorgio Santoni
, Roberto Pallini
, Lucia Ricci-Vitiani
, Emanuela Sabato
, Giulio Vistoli
, Fabio Del Bello
Research output
:
Contribution to journal
›
Article
›
peer-review
15
Scopus citations
Overview
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4
Receptor Antagonists Potentially Useful for the Treatment of Glioblastoma'. Together they form a unique fingerprint.
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Keyphrases
Dopamine
100%
Glioblastoma
100%
D4 Receptor
100%
High Affinity
50%
High Selectivity
50%
Receptor Antagonist
25%
New Ligand
25%
Propyl
25%
Brain Penetrant
25%
Cell Viability
25%
Glioma Stem Cells
25%
Glioblastoma Cell Lines
25%
Temozolomide
25%
Antitumor Activity
25%
Go Protein
25%
DRD4
25%
Biased Ligand
25%
Arrestin Recruitment
25%
Primary Glioblastoma
25%
Increased Effect
25%
2,3-dihydroquinazoline-4(1H)-one
25%
Pharmacology, Toxicology and Pharmaceutical Science
Glioblastoma
100%
Receptor
50%
Receptor Antagonist
16%
Antiinfective Agent
16%
Lead Compound
16%
Cell Viability
16%
Temozolomide
16%
Antitumor Activity
16%
Retina S Antigen
16%
Dopamine 4 Receptor
16%