Histiocytoses of the lung include a variety of diseases for which the unifying characteristic is the accumulation of histiocytic cells within lung parenchyma or air spaces. The diseases include macrophage and dendritic cell disorders as well as storage diseases that result in the accumulation of histiocytic cells in the lung. Pulmonary Langerhans' cell histiocytosis is the most common of these disorders. The histologic, radiologic, immunohistochemical, and, where relevant, ultrastructural characteristics of these diseases are compared in Table 16.1 and discussed in the various sections of this chapter.
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