History of fractures as predictor of subsequent hip and nonhip fractures among older Mexican Americans

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Abstract

Objective: To examine the association between previous fracture and risk of new hip and nonhip fractures over a seven-year period among older Mexican Americans. Method: Data used are from the Hispanic Established Population for the Epidemiological Study of the Elderly (H-EPESE) (1993-2001). Measures included history of previous fracture (hip fracture only, a nonhip fracture, hip and nonhip fractures, and no fractures), sociodemographic factors, smoking status, medical conditions (arthritis, diabetes, stroke and cancer), activities of daily living disability, and high depressive symptoms. Cox proportional regression model was used to estimate the seven-year incidence of fractures. Results: Of the 2,589 subjects, 42 reported a hip fracture, 328 reported a nonhip fracture, and 2,219 did not report a fracture at baseline. After controlling for all covariates, the hazard ratio (HR) of new hip fracture at seven-year follow-up was 6.48 (95 % CI: 3.26-12.97) for subjects with only hip fracture at baseline and 1.96 (95 % CI: 1.22-3.16) for subjects with nonhip fracture at baseline. The HR of new nonhip fracture was 1.90 (95 % CI: 0.96-3.77) for subjects with only hip fracture at baseline and 2.62 (95 % CI: 1.95-3.52) for subjects with nonhip fracture at baseline. Conclusions: A previous history of fractures in older Mexican Americans is the strongest predictor of recurrent fractures at hip and nonhip sites, independent of other health measures. Our findings of recurrent fractures suggest the need for more aggressive detection and adequate treatment of osteoporosis- and fall-related factors in this population.

Original languageEnglish (US)
Pages (from-to)412-418
Number of pages7
JournalJournal of the National Medical Association
Volume99
Issue number4
StatePublished - Apr 2007

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Hip Fractures
Activities of Daily Living
Hispanic Americans
Population
Osteoporosis
Arthritis
Epidemiologic Studies
Smoking
Stroke
Depression
Incidence
Health

Keywords

  • Elderly health
  • Fractures
  • Mexican Americans

ASJC Scopus subject areas

  • Medicine(all)

Cite this

@article{21c800d091aa4f58a9834cd91022e2a9,
title = "History of fractures as predictor of subsequent hip and nonhip fractures among older Mexican Americans",
abstract = "Objective: To examine the association between previous fracture and risk of new hip and nonhip fractures over a seven-year period among older Mexican Americans. Method: Data used are from the Hispanic Established Population for the Epidemiological Study of the Elderly (H-EPESE) (1993-2001). Measures included history of previous fracture (hip fracture only, a nonhip fracture, hip and nonhip fractures, and no fractures), sociodemographic factors, smoking status, medical conditions (arthritis, diabetes, stroke and cancer), activities of daily living disability, and high depressive symptoms. Cox proportional regression model was used to estimate the seven-year incidence of fractures. Results: Of the 2,589 subjects, 42 reported a hip fracture, 328 reported a nonhip fracture, and 2,219 did not report a fracture at baseline. After controlling for all covariates, the hazard ratio (HR) of new hip fracture at seven-year follow-up was 6.48 (95 {\%} CI: 3.26-12.97) for subjects with only hip fracture at baseline and 1.96 (95 {\%} CI: 1.22-3.16) for subjects with nonhip fracture at baseline. The HR of new nonhip fracture was 1.90 (95 {\%} CI: 0.96-3.77) for subjects with only hip fracture at baseline and 2.62 (95 {\%} CI: 1.95-3.52) for subjects with nonhip fracture at baseline. Conclusions: A previous history of fractures in older Mexican Americans is the strongest predictor of recurrent fractures at hip and nonhip sites, independent of other health measures. Our findings of recurrent fractures suggest the need for more aggressive detection and adequate treatment of osteoporosis- and fall-related factors in this population.",
keywords = "Elderly health, Fractures, Mexican Americans",
author = "Folasade Ojo and {Al Snih al snih}, Soham and Ray, {Laura A.} and Mukaila Raji and Kyriakos Markides",
year = "2007",
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pages = "412--418",
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T1 - History of fractures as predictor of subsequent hip and nonhip fractures among older Mexican Americans

AU - Ojo, Folasade

AU - Al Snih al snih, Soham

AU - Ray, Laura A.

AU - Raji, Mukaila

AU - Markides, Kyriakos

PY - 2007/4

Y1 - 2007/4

N2 - Objective: To examine the association between previous fracture and risk of new hip and nonhip fractures over a seven-year period among older Mexican Americans. Method: Data used are from the Hispanic Established Population for the Epidemiological Study of the Elderly (H-EPESE) (1993-2001). Measures included history of previous fracture (hip fracture only, a nonhip fracture, hip and nonhip fractures, and no fractures), sociodemographic factors, smoking status, medical conditions (arthritis, diabetes, stroke and cancer), activities of daily living disability, and high depressive symptoms. Cox proportional regression model was used to estimate the seven-year incidence of fractures. Results: Of the 2,589 subjects, 42 reported a hip fracture, 328 reported a nonhip fracture, and 2,219 did not report a fracture at baseline. After controlling for all covariates, the hazard ratio (HR) of new hip fracture at seven-year follow-up was 6.48 (95 % CI: 3.26-12.97) for subjects with only hip fracture at baseline and 1.96 (95 % CI: 1.22-3.16) for subjects with nonhip fracture at baseline. The HR of new nonhip fracture was 1.90 (95 % CI: 0.96-3.77) for subjects with only hip fracture at baseline and 2.62 (95 % CI: 1.95-3.52) for subjects with nonhip fracture at baseline. Conclusions: A previous history of fractures in older Mexican Americans is the strongest predictor of recurrent fractures at hip and nonhip sites, independent of other health measures. Our findings of recurrent fractures suggest the need for more aggressive detection and adequate treatment of osteoporosis- and fall-related factors in this population.

AB - Objective: To examine the association between previous fracture and risk of new hip and nonhip fractures over a seven-year period among older Mexican Americans. Method: Data used are from the Hispanic Established Population for the Epidemiological Study of the Elderly (H-EPESE) (1993-2001). Measures included history of previous fracture (hip fracture only, a nonhip fracture, hip and nonhip fractures, and no fractures), sociodemographic factors, smoking status, medical conditions (arthritis, diabetes, stroke and cancer), activities of daily living disability, and high depressive symptoms. Cox proportional regression model was used to estimate the seven-year incidence of fractures. Results: Of the 2,589 subjects, 42 reported a hip fracture, 328 reported a nonhip fracture, and 2,219 did not report a fracture at baseline. After controlling for all covariates, the hazard ratio (HR) of new hip fracture at seven-year follow-up was 6.48 (95 % CI: 3.26-12.97) for subjects with only hip fracture at baseline and 1.96 (95 % CI: 1.22-3.16) for subjects with nonhip fracture at baseline. The HR of new nonhip fracture was 1.90 (95 % CI: 0.96-3.77) for subjects with only hip fracture at baseline and 2.62 (95 % CI: 1.95-3.52) for subjects with nonhip fracture at baseline. Conclusions: A previous history of fractures in older Mexican Americans is the strongest predictor of recurrent fractures at hip and nonhip sites, independent of other health measures. Our findings of recurrent fractures suggest the need for more aggressive detection and adequate treatment of osteoporosis- and fall-related factors in this population.

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