Host Response to Implanted Dacron Grafts: A Comparison Between Mesh and Velour

Nicholas L. Tilney, Paul J. Boor

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

• Segments of open Dacron mesh grafts were subcutaneously implanted in rats and harvested for a period of up to 12 weeks after operation at serial intervals. The gross and histologic events of the host response to the external surface were compared to that of segments of low-porosity Dacron velour implanted in a similar fashion. Mature collagen, generously vascularized with new capillaries, was noted throughout the mesh within three to four weeks, while a tightly bonded inner fibrous layer had formed from the surrounding tissues. Major segments of velour floated in amorphous caseous material for up to five weeks. These pools of debris with their concomitant inflammatory response slowly resolved during a ten-week period. This prolonged healing may contribute to eventual graft closure by progressive fibrosis and extrinsic contracture.

Original languageEnglish (US)
Pages (from-to)1469-1472
Number of pages4
JournalArchives of Surgery
Volume110
Issue number12
DOIs
StatePublished - Dec 1975

ASJC Scopus subject areas

  • Surgery

Fingerprint Dive into the research topics of 'Host Response to Implanted Dacron Grafts: A Comparison Between Mesh and Velour'. Together they form a unique fingerprint.

  • Cite this