Host response to implanted Dacron grafts. A comparison between mesh and velour

N. L. Tilney, P. J. Boor

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Segments of open Dacron mesh grafts were subcutaneously implanted in rats and harvested for a period of up to 12 weeks after operation at serial intervals. The gross and histologic events of the host response to the external surface were compared to that of segments of low porosity Dacron velour implanted in a similar fashion. Mature collagen, generously vascularized with new capillaries, was noted throughout the mesh within three to four weeks, while a tightly bonded inner fibrous layer had formed from the surrounding tissues. Major segments of velour floated in amorphous caseous material for up to five weeks. These pools of debris with their concomitant inflammatory response slowly resolved during a ten week period. This prolonged healing may contribute to eventual graft closure by progressive fibrosis and extrinsic contracture.

Original languageEnglish (US)
Pages (from-to)1469-1472
Number of pages4
JournalArchives of Surgery
Volume110
Issue number12
StatePublished - 1975
Externally publishedYes

Fingerprint

Polyethylene Terephthalates
Transplants
Porosity
Contracture
Fibrosis
Collagen
velour

ASJC Scopus subject areas

  • Surgery

Cite this

Host response to implanted Dacron grafts. A comparison between mesh and velour. / Tilney, N. L.; Boor, P. J.

In: Archives of Surgery, Vol. 110, No. 12, 1975, p. 1469-1472.

Research output: Contribution to journalArticle

Tilney, NL & Boor, PJ 1975, 'Host response to implanted Dacron grafts. A comparison between mesh and velour', Archives of Surgery, vol. 110, no. 12, pp. 1469-1472.
Tilney, N. L. ; Boor, P. J. / Host response to implanted Dacron grafts. A comparison between mesh and velour. In: Archives of Surgery. 1975 ; Vol. 110, No. 12. pp. 1469-1472.
@article{613cec177eda419b93d43d7a7bc16384,
title = "Host response to implanted Dacron grafts. A comparison between mesh and velour",
abstract = "Segments of open Dacron mesh grafts were subcutaneously implanted in rats and harvested for a period of up to 12 weeks after operation at serial intervals. The gross and histologic events of the host response to the external surface were compared to that of segments of low porosity Dacron velour implanted in a similar fashion. Mature collagen, generously vascularized with new capillaries, was noted throughout the mesh within three to four weeks, while a tightly bonded inner fibrous layer had formed from the surrounding tissues. Major segments of velour floated in amorphous caseous material for up to five weeks. These pools of debris with their concomitant inflammatory response slowly resolved during a ten week period. This prolonged healing may contribute to eventual graft closure by progressive fibrosis and extrinsic contracture.",
author = "Tilney, {N. L.} and Boor, {P. J.}",
year = "1975",
language = "English (US)",
volume = "110",
pages = "1469--1472",
journal = "JAMA Surgery",
issn = "2168-6254",
publisher = "American Medical Association",
number = "12",

}

TY - JOUR

T1 - Host response to implanted Dacron grafts. A comparison between mesh and velour

AU - Tilney, N. L.

AU - Boor, P. J.

PY - 1975

Y1 - 1975

N2 - Segments of open Dacron mesh grafts were subcutaneously implanted in rats and harvested for a period of up to 12 weeks after operation at serial intervals. The gross and histologic events of the host response to the external surface were compared to that of segments of low porosity Dacron velour implanted in a similar fashion. Mature collagen, generously vascularized with new capillaries, was noted throughout the mesh within three to four weeks, while a tightly bonded inner fibrous layer had formed from the surrounding tissues. Major segments of velour floated in amorphous caseous material for up to five weeks. These pools of debris with their concomitant inflammatory response slowly resolved during a ten week period. This prolonged healing may contribute to eventual graft closure by progressive fibrosis and extrinsic contracture.

AB - Segments of open Dacron mesh grafts were subcutaneously implanted in rats and harvested for a period of up to 12 weeks after operation at serial intervals. The gross and histologic events of the host response to the external surface were compared to that of segments of low porosity Dacron velour implanted in a similar fashion. Mature collagen, generously vascularized with new capillaries, was noted throughout the mesh within three to four weeks, while a tightly bonded inner fibrous layer had formed from the surrounding tissues. Major segments of velour floated in amorphous caseous material for up to five weeks. These pools of debris with their concomitant inflammatory response slowly resolved during a ten week period. This prolonged healing may contribute to eventual graft closure by progressive fibrosis and extrinsic contracture.

UR - http://www.scopus.com/inward/record.url?scp=0016678774&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0016678774&partnerID=8YFLogxK

M3 - Article

VL - 110

SP - 1469

EP - 1472

JO - JAMA Surgery

JF - JAMA Surgery

SN - 2168-6254

IS - 12

ER -