Abstract
The nerve growth factor protein (NGF) isolated from mouse submaxillary gland has been shown to be necessary to the development of vertebrate sensory and sympathetic ganglia. Also, wide ranging alterations in the levels of NGF in the peripheral circulation of humans suffering from a variety of neuropathies have been reported. Many of these reports relied on the use of antibodies directed to the mouse β-NGF subunit for their quantitation of human NGF antigen. We report here on the lack of crossreaction between antibodies directed to mouse β-NGF and its human counterpart isolation from placenta at term.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 137-152 |
| Number of pages | 16 |
| Journal | Journal of Neuroscience Research |
| Volume | 8 |
| Issue number | 2-3 |
| State | Published - 1982 |
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ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Human β-nerve growth factor does not crossreact with antibodies to mouse β-nerve growth factor in a two-site radioimmunoassay. / Beck, C. E.; Perez Polo, J. R.
In: Journal of Neuroscience Research, Vol. 8, No. 2-3, 1982, p. 137-152.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Human β-nerve growth factor does not crossreact with antibodies to mouse β-nerve growth factor in a two-site radioimmunoassay
AU - Beck, C. E.
AU - Perez Polo, J. R.
PY - 1982
Y1 - 1982
N2 - The nerve growth factor protein (NGF) isolated from mouse submaxillary gland has been shown to be necessary to the development of vertebrate sensory and sympathetic ganglia. Also, wide ranging alterations in the levels of NGF in the peripheral circulation of humans suffering from a variety of neuropathies have been reported. Many of these reports relied on the use of antibodies directed to the mouse β-NGF subunit for their quantitation of human NGF antigen. We report here on the lack of crossreaction between antibodies directed to mouse β-NGF and its human counterpart isolation from placenta at term.
AB - The nerve growth factor protein (NGF) isolated from mouse submaxillary gland has been shown to be necessary to the development of vertebrate sensory and sympathetic ganglia. Also, wide ranging alterations in the levels of NGF in the peripheral circulation of humans suffering from a variety of neuropathies have been reported. Many of these reports relied on the use of antibodies directed to the mouse β-NGF subunit for their quantitation of human NGF antigen. We report here on the lack of crossreaction between antibodies directed to mouse β-NGF and its human counterpart isolation from placenta at term.
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UR - http://www.scopus.com/inward/citedby.url?scp=0020422720&partnerID=8YFLogxK
M3 - Article
VL - 8
SP - 137
EP - 152
JO - Journal of Neuroscience Research
JF - Journal of Neuroscience Research
SN - 0360-4012
IS - 2-3
ER -