Human bocavirus infection in children with acute respiratory tract infection in India

Preeti Bharaj, Wayne M. Sullender, Sushil K. Kabra, Shobha Broor

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

Human bocavirus (HBoV) is a new human parvovirus identified in children with respiratory tract disease. Nasopharyngeal aspirates were collected from 305 children <5 years of age with acute respiratory tract infection from April 2005 to March 2007 and screened for the presence of HBoV by two separate sets of a polymerase chain reaction (PCR) described previously. Twenty-two (7.2%) children who had acute respiratory infection were found to be positive for HBoV by both sets of PCR. The main clinical symptoms were cough (95%), runny nose (64%), and fever (59%). In two samples, HBoV was identified together with respiratory syncytial virus in one sample and influenza A virus in another. HBoV appeared to have no seasonal distribution and is associated with both upper and lower respiratory tract disease in young children in India.

Original languageEnglish (US)
Pages (from-to)812-816
Number of pages5
JournalJournal of Medical Virology
Volume82
Issue number5
DOIs
StatePublished - May 1 2010

Keywords

  • Acute respiratory infections
  • Clinical symptoms
  • Human bocavirus
  • Polymerase chain reaction

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

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