Abstract
The SF strain of human herpesvirus 6 (HHV-6(SF)) isolated from the saliva of a human immunodeficiency virus (HIV)-infected individual was shown to inhibit HIV type 1 (HIV-1) replication in both peripheral blood mononuclear cells and purified CD4+ lymphocytes. This suppression of HIV-1 replication led to decreased cytopathic effects of HIV-1 and prolonged survival of CD4+ cells in culture. Even low levels of HHV-6 added to peripheral blood mononuclear cells showed an inhibitory effect an inhibitory effect on HIV-1 replication. These results differ from those previously reported showing enhanced HIV-1 production following infection with another strain of HHV-6.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2362-2364 |
| Number of pages | 3 |
| Journal | Journal of Clinical Microbiology |
| Volume | 28 |
| Issue number | 10 |
| DOIs | |
| State | Published - 1990 |
| Externally published | Yes |
ASJC Scopus subject areas
- Microbiology (medical)
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