Human-rodent contact and infection with lymphocytic choriomeningitis and Seoul viruses in an inner-city population

J. E. Childs, G. E. Glass, Thomas Ksiazek, C. A. Rossi, J. G B Oro, James LeDuc

Research output: Contribution to journalArticle

99 Citations (Scopus)

Abstract

We collected 1180 sera and 1363 questionnaires with information on demography, rodent exposure, and history of travel from persons visiting a sexually transmitted disease (STD) clinic in Baltimore between 1986-1988. Serological tests for two rodent-borne viruses detected antibodies to lymphocytic choriomeningitis virus (LCMV) in 54 individuals (4.70%; n=1149) and antibodies to Seoul virus (SEOV) in three persons (0.25%; n=1180). Antibody prevalence to LCMV increased with age, but there were no racial or sexual differences. Neutralization tests and questionnaire responses implicated a domestic, rat-borne hantavirus as the source of SEOV antibody. Self-reported human-rodent contact indicated more exposure to house mice than rats within residences, although rats were more commonly sighted on streets. Infections with rodent-borne viruses were rare compared to the high rates of reported contact.

Original languageEnglish (US)
Pages (from-to)117-121
Number of pages5
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume44
Issue number2
StatePublished - 1991
Externally publishedYes

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Seoul virus
Lymphocytic choriomeningitis virus
Rodentia
Antibodies
Infection
Population
Hantavirus
Viruses
Neutralization Tests
Baltimore
Serologic Tests
Sexually Transmitted Diseases
Demography
Serum

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Human-rodent contact and infection with lymphocytic choriomeningitis and Seoul viruses in an inner-city population. / Childs, J. E.; Glass, G. E.; Ksiazek, Thomas; Rossi, C. A.; Oro, J. G B; LeDuc, James.

In: American Journal of Tropical Medicine and Hygiene, Vol. 44, No. 2, 1991, p. 117-121.

Research output: Contribution to journalArticle

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