Human Trypanosoma cruzi infection and seropositivity in dogs, Mexico

Jose G. Estrada-Franco, Vandanajay Bhatia, Hector Diaz-Albiter, Laucel Ochoa-Garcia, Alberto Barbabosa, Juan C. Vazquez-Chagoyan, Miguel A. Martinez-Perez, Carmen Guzman-Bracho, Nisha Garg

Research output: Contribution to journalArticlepeer-review

106 Scopus citations


We used 5 diagnostic tests in a cross-sectional investigation of the prevalence of Trypanosoma cruzi in Tejupilco municipality, State of Mexico, Mexico. Our findings showed a substantial prevalence of immunoglobulin G (IgG) and IgM antibodies to T. cruzi in human (n = 293, IgG 2.05%, IgM 5.5%, both 7.1%) and dog (n = 114, IgG 15.8%, IgM 11.4%, both 21%) populations. We also found antibodies to T. cruzi (n = 80, IgG 10%, IgM 15%, both 17.5%) in dogs from Toluca, an area previously considered free of T. cruzi. Our data demonstrate the need for active epidemiologic surveillance programs in these regions. A direct correlation (r2 = 0.955) of seropositivity between humans and dogs suggests that seroanalysis in dogs may help identify the human prevalence of T. cruzi infection in these areas.

Original languageEnglish (US)
Pages (from-to)624-630
Number of pages7
JournalEmerging infectious diseases
Issue number4
StatePublished - Apr 2006

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases


Dive into the research topics of 'Human Trypanosoma cruzi infection and seropositivity in dogs, Mexico'. Together they form a unique fingerprint.

Cite this