Hunting in the rainforest and mayaro virus infection

An emerging alphavirus in Ecuador

Ricardo O. Izurieta, Maurizio MacAluso, Douglas M. Watts, Robert B. Tesh, Bolivar Guerra, Ligia M. Cruz, Sagar Galwankar, Sten H. Vermund

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Objectives: The objectives of this report were to document the potential presence of Mayaro virus infection in Ecuador and to examine potential risk factors for Mayaro virus infection among the personnel of a military garrison in the Amazonian rainforest. Materials and Methods: The study population consisted of the personnel of a garrison located in the Ecuadorian Amazonian rainforest. The cross-sectional study employed interviews and seroepidemiological methods. Humoral immune response to Mayaro virus infection was assessed by evaluating IgM- and IgG-specific antibodies using ELISA. Results: Of 338 subjects studied, 174 were from the Coastal zone of Ecuador, 73 from Andean zone, and 91 were native to the Amazonian rainforest. Seroprevalence of Mayaro virus infection was more than 20 times higher among Amazonian natives (46%) than among subjects born in other areas (2%). Conclusions: Age and hunting in the rainforest were significant predictors of Mayaro virus infection overall and among Amazonian natives. The results provide the first demonstration of the potential presence of Mayaro virus infection in Ecuador and a systematic evaluation of risk factors for the transmission of this alphavirus. The large difference in prevalence rates between Amazonian natives and other groups and between older and younger natives suggest that Mayaro virus is endemic and enzootic in the rainforest, with sporadic outbreaks that determine differences in risk between birth cohorts of natives. Deep forest hunting may selectively expose native men, descendants of the Shuar and Huaronai ethnic groups, to the arthropod vectors of Mayaro virus in areas close to primate reservoirs.

Original languageEnglish
Pages (from-to)317-323
Number of pages7
JournalJournal of Global Infectious Diseases
Volume3
Issue number4
DOIs
StatePublished - Oct 2011

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Alphavirus
Ecuador
Virus Diseases
Population Groups
Arthropod Vectors
Viruses
Military Personnel
Seroepidemiologic Studies
Humoral Immunity
Ethnic Groups
Primates
Disease Outbreaks
Immunoglobulin M
Rainforest
Cross-Sectional Studies
Immunoglobulin G
Enzyme-Linked Immunosorbent Assay
Parturition
Interviews
Antibodies

Keywords

  • Alphavirus
  • Amazon
  • Ecuador
  • Mayaro virus

ASJC Scopus subject areas

  • Infectious Diseases

Cite this

Izurieta, R. O., MacAluso, M., Watts, D. M., Tesh, R. B., Guerra, B., Cruz, L. M., ... Vermund, S. H. (2011). Hunting in the rainforest and mayaro virus infection: An emerging alphavirus in Ecuador. Journal of Global Infectious Diseases, 3(4), 317-323. https://doi.org/10.4103/0974-777X.91049

Hunting in the rainforest and mayaro virus infection : An emerging alphavirus in Ecuador. / Izurieta, Ricardo O.; MacAluso, Maurizio; Watts, Douglas M.; Tesh, Robert B.; Guerra, Bolivar; Cruz, Ligia M.; Galwankar, Sagar; Vermund, Sten H.

In: Journal of Global Infectious Diseases, Vol. 3, No. 4, 10.2011, p. 317-323.

Research output: Contribution to journalArticle

Izurieta, RO, MacAluso, M, Watts, DM, Tesh, RB, Guerra, B, Cruz, LM, Galwankar, S & Vermund, SH 2011, 'Hunting in the rainforest and mayaro virus infection: An emerging alphavirus in Ecuador', Journal of Global Infectious Diseases, vol. 3, no. 4, pp. 317-323. https://doi.org/10.4103/0974-777X.91049
Izurieta, Ricardo O. ; MacAluso, Maurizio ; Watts, Douglas M. ; Tesh, Robert B. ; Guerra, Bolivar ; Cruz, Ligia M. ; Galwankar, Sagar ; Vermund, Sten H. / Hunting in the rainforest and mayaro virus infection : An emerging alphavirus in Ecuador. In: Journal of Global Infectious Diseases. 2011 ; Vol. 3, No. 4. pp. 317-323.
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