Hyaline cells in a benign chondroid syringoma: Report of a case and findings by conventional and electron microscopy

Nobby Mambo

Research output: Contribution to journalArticle

18 Scopus citations


This report describes the features of a benign chondroid syringoma removed from a foot of a 34-year-old woman. Histologic examination showed that an acidophilic hyaline cells was the predominant cell type; keratocytes and cells with clear to foamy cytoplasms were less abundant. The hyaline cells and keratinocytes were within a chondroid and myxoid stroma. Ultrastructural study revealed large numbers of pale epithelial cells whose cytoplasms were loaded with intermediate filaments and dark cells with many tonofilaments. Intermediate transition forms between the pale and dark cells were also identified, as were myoepithelial cells with intermediate filaments, and secretory cells. These cells were also lodged in a chondroid and myxoid matrix. This study showed that acidophilic hyaline cells are of both epithelial and myoepithelial origin and that both may be responsible for laying down the matrix.

Original languageEnglish (US)
Pages (from-to)265-272
Number of pages8
JournalAmerican Journal of Dermatopathology
Issue number3
StatePublished - 1984
Externally publishedYes


ASJC Scopus subject areas

  • Dermatology
  • Pathology and Forensic Medicine

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