Hyalinizing clear cell carcinoma of the tonsil and its treatment

Shadi B. Hijjawi, Shaad E. Abdullah, Kareem Abdelhadi, Eduardo Eyzaguirre, Maurice Willis, Nihal E. Abdulla

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Hyalinizing clear cell carcinoma (HCCC) is a rare neoplasm affecting mainly the minor salivary glands of the oral cavity. We describe an unusual case of HCCC involving the tonsil and its successful management. A 67-year-old Hispanic woman was discovered to have an asymptomatic right tonsillar mass on routine clinic visit that revealed HCCC on biopsy. A right radical tonsillectomy was performed and pathology confirmed HCCC with positive deep surgical margins. She declined the recommended adjuvant radiation therapy. A follow-up CT of the neck with contrast done a year later revealed a suspicious area of enhancement around the prior resection margin with regional cervical lymphadenopathy. Further workup, including biopsy, confirmed local recurrence. She was treated with definitive cisplatin-based chemoradiotherapy, achieving complete response. She remains without recurrence with more than 24 months of follow-up.

Original languageEnglish (US)
JournalOral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Volume114
Issue number2
DOIs
StatePublished - Aug 2012

Fingerprint

Palatine Tonsil
Carcinoma
Minor Salivary Glands
Biopsy
Recurrence
Tonsillectomy
Chemoradiotherapy
Therapeutics
Ambulatory Care
Hispanic Americans
Cisplatin
Mouth
Neck
Radiotherapy
Pathology
Neoplasms
Margins of Excision

ASJC Scopus subject areas

  • Surgery
  • Oral Surgery
  • Pathology and Forensic Medicine
  • Radiology Nuclear Medicine and imaging
  • Dentistry (miscellaneous)

Cite this

Hyalinizing clear cell carcinoma of the tonsil and its treatment. / Hijjawi, Shadi B.; Abdullah, Shaad E.; Abdelhadi, Kareem; Eyzaguirre, Eduardo; Willis, Maurice; Abdulla, Nihal E.

In: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Vol. 114, No. 2, 08.2012.

Research output: Contribution to journalArticle

Hijjawi, Shadi B. ; Abdullah, Shaad E. ; Abdelhadi, Kareem ; Eyzaguirre, Eduardo ; Willis, Maurice ; Abdulla, Nihal E. / Hyalinizing clear cell carcinoma of the tonsil and its treatment. In: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2012 ; Vol. 114, No. 2.
@article{03856200bfa04f07adea02412a72def7,
title = "Hyalinizing clear cell carcinoma of the tonsil and its treatment",
abstract = "Hyalinizing clear cell carcinoma (HCCC) is a rare neoplasm affecting mainly the minor salivary glands of the oral cavity. We describe an unusual case of HCCC involving the tonsil and its successful management. A 67-year-old Hispanic woman was discovered to have an asymptomatic right tonsillar mass on routine clinic visit that revealed HCCC on biopsy. A right radical tonsillectomy was performed and pathology confirmed HCCC with positive deep surgical margins. She declined the recommended adjuvant radiation therapy. A follow-up CT of the neck with contrast done a year later revealed a suspicious area of enhancement around the prior resection margin with regional cervical lymphadenopathy. Further workup, including biopsy, confirmed local recurrence. She was treated with definitive cisplatin-based chemoradiotherapy, achieving complete response. She remains without recurrence with more than 24 months of follow-up.",
author = "Hijjawi, {Shadi B.} and Abdullah, {Shaad E.} and Kareem Abdelhadi and Eduardo Eyzaguirre and Maurice Willis and Abdulla, {Nihal E.}",
year = "2012",
month = "8",
doi = "10.1016/j.oooo.2012.02.003",
language = "English (US)",
volume = "114",
journal = "Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology",
issn = "2212-4403",
publisher = "Elsevier USA",
number = "2",

}

TY - JOUR

T1 - Hyalinizing clear cell carcinoma of the tonsil and its treatment

AU - Hijjawi, Shadi B.

AU - Abdullah, Shaad E.

AU - Abdelhadi, Kareem

AU - Eyzaguirre, Eduardo

AU - Willis, Maurice

AU - Abdulla, Nihal E.

PY - 2012/8

Y1 - 2012/8

N2 - Hyalinizing clear cell carcinoma (HCCC) is a rare neoplasm affecting mainly the minor salivary glands of the oral cavity. We describe an unusual case of HCCC involving the tonsil and its successful management. A 67-year-old Hispanic woman was discovered to have an asymptomatic right tonsillar mass on routine clinic visit that revealed HCCC on biopsy. A right radical tonsillectomy was performed and pathology confirmed HCCC with positive deep surgical margins. She declined the recommended adjuvant radiation therapy. A follow-up CT of the neck with contrast done a year later revealed a suspicious area of enhancement around the prior resection margin with regional cervical lymphadenopathy. Further workup, including biopsy, confirmed local recurrence. She was treated with definitive cisplatin-based chemoradiotherapy, achieving complete response. She remains without recurrence with more than 24 months of follow-up.

AB - Hyalinizing clear cell carcinoma (HCCC) is a rare neoplasm affecting mainly the minor salivary glands of the oral cavity. We describe an unusual case of HCCC involving the tonsil and its successful management. A 67-year-old Hispanic woman was discovered to have an asymptomatic right tonsillar mass on routine clinic visit that revealed HCCC on biopsy. A right radical tonsillectomy was performed and pathology confirmed HCCC with positive deep surgical margins. She declined the recommended adjuvant radiation therapy. A follow-up CT of the neck with contrast done a year later revealed a suspicious area of enhancement around the prior resection margin with regional cervical lymphadenopathy. Further workup, including biopsy, confirmed local recurrence. She was treated with definitive cisplatin-based chemoradiotherapy, achieving complete response. She remains without recurrence with more than 24 months of follow-up.

UR - http://www.scopus.com/inward/record.url?scp=84863605945&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84863605945&partnerID=8YFLogxK

U2 - 10.1016/j.oooo.2012.02.003

DO - 10.1016/j.oooo.2012.02.003

M3 - Article

VL - 114

JO - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

JF - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

SN - 2212-4403

IS - 2

ER -