Hypoxia potentiates the capacity of melanoma cells to evade cisplatin and doxorubicin cytotoxicity via glycolytic shift

Keyphrases

• Cisplatin 100%
• Cytotoxicity 100%
• Hypoxia 100%
• Melanoma Cells 100%
• Doxorubicin 100%
• Evade 100%
• Glycolytic Shift 100%
• Vulnerability 66%
• Melanoma 66%
• Mitochondrial DNA 33%
• Glycolytic Metabolism 33%
• Mitochondrial Respiration 33%
• Cell-derived 33%
• Solid Tumors 33%
• Chemotherapeutic Treatment 33%
• Metabolic Reprogramming 33%
• Hypoxic Environment 33%
• Melanocytic Tumor 33%
• Proliferating Cells 33%
• Genetic Makeup 33%
• Human-relevant 33%
• Cell Death Rate 33%
• Anticancer Treatment 33%
• B16F10 Cells 33%
• Driver mutations 33%
• Proliferative Arrest 33%

Medicine and Dentistry

• Hypoxia 100%
• Cytotoxicity 100%
• Nodular Melanoma 100%
• Melanoma Cell 100%
• Doxorubicin 100%
• Cisplatin 100%
• Mortality Rate 33%
• Neoplasm 33%
• Chemotherapy 33%
• Cell Death 33%
• Mitochondrial Respiration 33%
• Solid Malignant Neoplasm 33%
• Engineered Cell 33%
• Mitochondrial DNA Depletion 33%

Biochemistry, Genetics and Molecular Biology

• Cytotoxicity 100%
• Cisplatin 100%
• Doxorubicin 100%
• Metabolic Pathway 33%
• Genetics 33%
• Cell Death 33%
• Mitochondrial Respiration 33%
• Anticancer 33%
• Reprogramming 33%
• Mortality Rate 33%
• Mitochondrial DNA Depletion 33%