Ia antigen on the surface of a subfraction of T cells that bear Fc receptors for IgG

P. A. Kaszubowski, James Goodwin, R. C. Williams

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

Human peripheral blood T cells and T cell subpopulations were studied for the presence of Ia-like antigen, by using indirect immunofluorescence with heterologous rabbit anti-Ia antisera. In 13 normal subjects the percentage of T cells staining with the anti-Ia reagent was 2 to 5% and appeared limited to the Tγ subfraction. After concanavalin A or phytohemagglutinin activation, the proportion of Ia(+) T cells increased due to an increase in the percentage of Tγ cells bearing Ia-like antigen as well as an increase in the proportion of Tγ cells in the T cell fraction.

Original languageEnglish (US)
Pages (from-to)1075-1078
Number of pages4
JournalJournal of Immunology
Volume124
Issue number3
StatePublished - 1980
Externally publishedYes

    Fingerprint

ASJC Scopus subject areas

  • Immunology

Cite this