Human peripheral blood T cells and T cell subpopulations were studied for the presence of Ia-like antigen, by using indirect immunofluorescence with heterologous rabbit anti-Ia antisera. In 13 normal subjects the percentage of T cells staining with the anti-Ia reagent was 2 to 5% and appeared limited to the Tγ subfraction. After concanavalin A or phytohemagglutinin activation, the proportion of Ia(+) T cells increased due to an increase in the percentage of Tγ cells bearing Ia-like antigen as well as an increase in the proportion of Tγ cells in the T cell fraction.
|Original language||English (US)|
|Number of pages||4|
|Journal||Journal of Immunology|
|State||Published - 1980|
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