Ia antigen on the surface of a subfraction of T cells that bear Fc receptors for IgG

P. A. Kaszubowski, James Goodwin, R. C. Williams

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Human peripheral blood T cells and T cell subpopulations were studied for the presence of Ia-like antigen, by using indirect immunofluorescence with heterologous rabbit anti-Ia antisera. In 13 normal subjects the percentage of T cells staining with the anti-Ia reagent was 2 to 5% and appeared limited to the Tγ subfraction. After concanavalin A or phytohemagglutinin activation, the proportion of Ia(+) T cells increased due to an increase in the percentage of Tγ cells bearing Ia-like antigen as well as an increase in the proportion of Tγ cells in the T cell fraction.

Original languageEnglish (US)
Pages (from-to)1075-1078
Number of pages4
JournalJournal of Immunology
Volume124
Issue number3
StatePublished - 1980
Externally publishedYes

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Fc Receptors
Histocompatibility Antigens Class II
Immunoglobulin G
T-Lymphocytes
Phytohemagglutinins
Indirect Fluorescent Antibody Technique
Concanavalin A
Immune Sera
Blood Cells
Staining and Labeling
Rabbits

ASJC Scopus subject areas

  • Immunology

Cite this

Ia antigen on the surface of a subfraction of T cells that bear Fc receptors for IgG. / Kaszubowski, P. A.; Goodwin, James; Williams, R. C.

In: Journal of Immunology, Vol. 124, No. 3, 1980, p. 1075-1078.

Research output: Contribution to journalArticle

Kaszubowski, P. A. ; Goodwin, James ; Williams, R. C. / Ia antigen on the surface of a subfraction of T cells that bear Fc receptors for IgG. In: Journal of Immunology. 1980 ; Vol. 124, No. 3. pp. 1075-1078.
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