Identification and analysis of phosphopeptides

Michael J. Chalmers; Walter Kolch; Mark R. Emmett; Alan G. Marshall; Harald Mischak

doi:10.1016/j.jchromb.2003.09.006

Identification and analysis of phosphopeptides

Michael J. Chalmers
, Walter Kolch
, Mark R. Emmett
, Alan G. Marshall
, Harald Mischak

Research output: Contribution to journal › Review article › peer-review

64 Scopus citations

Abstract

Reversible phosphorylation of serine, threonine and tyrosine residues in proteins is one of the key events in signal transduction. To understand the process of signal transduction on a molecular level, it is imperative to identify phosphorylation sites in proteins. In this review, we offer an overview of the different methods/technologies currently available to identify protein phosphorylation sites.

Original language	English (US)
Pages (from-to)	111-120
Number of pages	10
Journal	Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
Volume	803
Issue number	1
DOIs	https://doi.org/10.1016/j.jchromb.2003.09.006
State	Published - Apr 15 2004
Externally published	Yes

Keywords

Phosphopeptides
Phosphorylation
Post-translational modification
Reviews

ASJC Scopus subject areas

Biochemistry

Access to Document

10.1016/j.jchromb.2003.09.006

Cite this

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title = "Identification and analysis of phosphopeptides",

abstract = "Reversible phosphorylation of serine, threonine and tyrosine residues in proteins is one of the key events in signal transduction. To understand the process of signal transduction on a molecular level, it is imperative to identify phosphorylation sites in proteins. In this review, we offer an overview of the different methods/technologies currently available to identify protein phosphorylation sites.",

keywords = "Phosphopeptides, Phosphorylation, Post-translational modification, Reviews",

author = "Chalmers, \{Michael J.\} and Walter Kolch and Emmett, \{Mark R.\} and Marshall, \{Alan G.\} and Harald Mischak",

note = "Funding Information: HM acknowledges support from the BioProfil “Funktionelle Genomanalyse”, Germany. MJC, MRE and AGM acknowledge the NSF National High-Field FT-ICR Facility (CHE-99-09502), Florida State University, and the National High Magnetic Field Laboratory in Tallahassee, Florida. WK acknowledges support from the Wellcome Trust and Cancer Research, UK. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.",

year = "2004",

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day = "15",

doi = "10.1016/j.jchromb.2003.09.006",

language = "English (US)",

volume = "803",

pages = "111--120",

journal = "Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences",

issn = "1570-0232",

publisher = "Elsevier BV",

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T1 - Identification and analysis of phosphopeptides

AU - Chalmers, Michael J.

AU - Kolch, Walter

AU - Emmett, Mark R.

AU - Marshall, Alan G.

AU - Mischak, Harald

N1 - Funding Information: HM acknowledges support from the BioProfil “Funktionelle Genomanalyse”, Germany. MJC, MRE and AGM acknowledge the NSF National High-Field FT-ICR Facility (CHE-99-09502), Florida State University, and the National High Magnetic Field Laboratory in Tallahassee, Florida. WK acknowledges support from the Wellcome Trust and Cancer Research, UK. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.

PY - 2004/4/15

Y1 - 2004/4/15

N2 - Reversible phosphorylation of serine, threonine and tyrosine residues in proteins is one of the key events in signal transduction. To understand the process of signal transduction on a molecular level, it is imperative to identify phosphorylation sites in proteins. In this review, we offer an overview of the different methods/technologies currently available to identify protein phosphorylation sites.

AB - Reversible phosphorylation of serine, threonine and tyrosine residues in proteins is one of the key events in signal transduction. To understand the process of signal transduction on a molecular level, it is imperative to identify phosphorylation sites in proteins. In this review, we offer an overview of the different methods/technologies currently available to identify protein phosphorylation sites.

KW - Phosphopeptides

KW - Phosphorylation

KW - Post-translational modification

KW - Reviews

UR - https://www.scopus.com/pages/publications/1542509479

UR - https://www.scopus.com/pages/publications/1542509479#tab=citedBy

U2 - 10.1016/j.jchromb.2003.09.006

DO - 10.1016/j.jchromb.2003.09.006

M3 - Review article

C2 - 15026004

AN - SCOPUS:1542509479

SN - 1570-0232

VL - 803

SP - 111

EP - 120

JO - Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

JF - Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

IS - 1

ER -

Identification and analysis of phosphopeptides

Abstract

Keywords

ASJC Scopus subject areas

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