Identification and quantification of human brown adipose tissue

Maria Chondronikola, Craig Porter, John O. Ogunbileje, Labros S. Sidossis

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations


Brown adipose tissue (BAT) has attracted significant interest as a potential target tissue against obesity and its associated metabolic perturbations. The purpose of this chapter is to provide an overview of some of the methodological approaches that can be used to identify and quantify BAT in people. Specifically, we will provide a step-by-step description of the following procedures: quantification of BAT in vivo using positron emission tomography-computed tomography (PET/CT) with 2-deoxy-2-[18F]fluoroglucose (18F-FDG) as a tracer, mitochondrial respiration, and uncoupling protein 1 (UCP1) gene and protein expression.

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Number of pages18
StatePublished - 2017

Publication series

NameMethods in Molecular Biology
ISSN (Print)1064-3745


  • 2-deoxy-2-[F]fluoroglucose
  • Biopsy
  • Brown adipose tissue
  • Positron emission tomography-computed tomography
  • Uncoupling protein 1

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics


Dive into the research topics of 'Identification and quantification of human brown adipose tissue'. Together they form a unique fingerprint.

Cite this