Keyphrases
Amino Acid Residues
100%
Structure Function
100%
Fn14
100%
Voltage-gated Sodium Channel
100%
Sodium Channel Nav1.6
100%
Nav1.6
20%
Dimer Formation
20%
Protein-protein Interaction
13%
Protein-protein Interface
13%
Alanine mutation
13%
Drug Development
6%
Allosteric Modulator
6%
N-terminus
6%
Activation State
6%
Purified Proteins
6%
Nav Channels
6%
Voltage-gated Channels
6%
Na +
6%
Tissue-engineered Constructs
6%
Homodimer
6%
Divergence
6%
Stronger Binding
6%
Gating Properties
6%
Whole-cell Patch-clamp Electrophysiology
6%
Electrical Excitability
6%
NaV1.6 Channels
6%
Channel Expression
6%
Accessory Protein
6%
Steady-state Inactivation
6%
Luciferase Assay
6%
Intrinsic Fluorescence Spectroscopy
6%
Channel Gating
6%
Fast Inactivation
6%
Expression Property
6%
Voltage-dependent Activation
6%
Intrinsic Excitability
6%
Guided mutation
6%
Model-guided
6%
Biochemistry, Genetics and Molecular Biology
Amino Acids
100%
Electric Potential
100%
Fibroblast Growth Factor
100%
Sodium Channel
100%
Dimerization
20%
Protein-Protein Interaction
13%
N-Terminus
13%
Excitability
13%
Alanine
13%
Steady State
6%
Luciferase
6%
Electrophysiology
6%
Whole Cell Patch Clamp
6%
Channel Gating
6%
Fluorescence Spectroscopy
6%
Drug Development
6%
Medicine and Dentistry
Amino Acid
100%
Sodium Channel Nav1.6
100%
Fibroblast Growth Factor 14
100%
Dimer
20%
Excitability
13%
Sodium Ion
13%
Tail
13%
Alanine
13%
Amino Terminal Sequence
13%
Protein-Protein Interaction
13%
Spectrofluorometry
6%
Patch Clamp
6%
Steady State
6%
Allosteric Modulator
6%
Whole Cell
6%
Electrophysiology
6%
Channel Gating
6%
Homodimer
6%
Luciferase Assay
6%
Neuroscience
Amino Acid
100%
Fibroblast Growth Factor 14
100%
Sodium Channel Nav1.6
100%
Amino Terminal Sequence
13%
Protein-Protein Interaction
13%
Alanine
13%
Patch Clamp
6%
Excitability
6%
Luciferase
6%
Channel Gating
6%
Spectroscopy
6%
Electrophysiology
6%
Intrinsic Excitability
6%
Pharmacology, Toxicology and Pharmaceutical Science
Amino Acid
100%
Fibroblast Growth Factor 14
100%
Sodium Channel Nav1.6
100%
Dimer
20%
Sodium Ion
13%
Alanine
13%
Drug Development
6%
Allosteric Modulator
6%
Luciferase
6%
Homodimer
6%