Identification of cardiac oxidoreductase(s) involved in the metabolism of the lipid peroxidation-derived aldehyde-4-hydroxynonenal

Keyphrases

• Metabolism 100%
• 4-hydroxynonenal (4-HNE) 100%
• Lipid Peroxidation 100%
• Aldehydes 100%
• 4-hydroxy-2 100%
• Oxidoreductase 100%
• Aldose Reductase 35%
• IC50 11%
• Fold Increase 5%
• Alcohol Dehydrogenase 5%
• Oxidative Stress 5%
• Alcohol 5%
• Amino Acid Sequence 5%
• Sequence Analysis 5%
• High Affinity 5%
• Antioxidant Enzymes 5%
• Myocardial Protection 5%
• Sorbinil 5%
• Immunological Properties 5%
• Kinetic Properties 5%
• Apoenzyme 5%
• Incubation 5%
• Cardiac Enzymes 5%
• Fibroblast Growth Factor 1 (FGF1) 5%
• Unsaturated Aldehyde 5%
• Purified Enzymes 5%
• Polyunsaturated Fatty Acids 5%
• Radiolabeled Peptides 5%
• Polyol Pathway Enzymes 5%
• Product Inhibition 5%
• Pyridine 5%
• Ventricle 5%
• Modified Peptide 5%
• Glyceraldehyde 5%
• Bovine Heart 5%
• Peroxidation 5%
• NADPH-dependent Enzyme 5%
• Partial Modification 5%
• Mediated Catalysis 5%
• Mouse Vas Deferens 5%
• NADPH Oxidation 5%
• Modified Enzymes 5%
• Irreversible Loss 5%

Biochemistry, Genetics and Molecular Biology

• Metabolic Pathway 100%
• Enzyme 100%
• Oxidoreductase 100%
• Lipid Peroxidation 100%
• Aldose Reductase 46%
• Alpha Oxidation 15%
• IC50 15%
• Nicotinamide Adenine Dinucleotide Phosphate 15%
• Alcohol Dehydrogenase 7%
• Mouse 7%
• Oxidative Stress 7%
• Homogenate 7%
• Peptide Sequence 7%
• Protein Sequencing 7%
• Polyol Pathway 7%
• Fibroblast Growth Factor 7%
• Product Inhibition 7%
• Polyunsaturated Fatty Acid 7%
• Tolrestat 7%
• Glyceraldehyde 7%
• Coenzyme 7%
• Peroxidation 7%
• NADPH-dependent Enzymes 7%

Pharmacology, Toxicology and Pharmaceutical Science

• 4 Hydroxynonenal 100%
• Oxidoreductase 100%
• Aldehyde Reductase 33%
• Reduced Nicotinamide Adenine Dinucleotide Phosphate 11%
• Nicotinamide Adenine Dinucleotide Phosphate 11%
• IC50 11%
• Ethanol 5%
• Alcohol Dehydrogenase 5%
• Mouse 5%
• Amino Acid 5%
• Antioxidant 5%
• Aldehyde 5%
• Polyol 5%
• Apoenzyme 5%
• Sorbinil 5%
• Polyunsaturated Fatty Acid 5%
• Tolrestat 5%
• Fibroblast Growth Factor 5%
• Glyceraldehyde 5%