Identification of compounds with anti-West Nile virus activity

Keyphrases

• West Nile Virus 100%
• Virus Activity 100%
• Viral Replication 28%
• Thiophen 28%
• Pyrazoline 28%
• 4,5-Dihydro-1H-pyrazole 28%
• Replication Protein A 14%
• Mechanism of Action 14%
• Flavivirus 14%
• Structural Requirements 14%
• Yellow Fever 14%
• Small Molecules 14%
• RNA Synthesis 14%
• Replicon 14%
• Antiviral Compounds 14%
• Physicochemical Properties 14%
• Viral Titer 14%
• Dengue Fever 14%
• Viral RNA Polymerase 14%
• Therapeutic Index 14%
• RNA Helicase 14%
• Quinoline 14%
• Cell Viability 14%
• Epidemic Strain 14%
• Combinatorial Library 14%
• 1H-1 14%
• Nitrophenyl 14%
• Chlorophenyl 14%
• Cytotoxicity Assay 14%
• Reduction Test 14%
• Structural Class 14%
• Benzoyl 14%
• Aryl Rings 14%
• SAR Data 14%
• Acridine 14%
• Titer Reduction 14%
• Reporting System 14%
• Problems in the Development 14%
• High Throughput Screening Techniques 14%
• Focused Chemical Library 14%
• Substituted Pyrazolines 14%
• Aryl Substitution 14%
• Triaryl Pyrazoline 14%
• Xanthane 14%

Chemistry

• Ribonucleic Acid 100%
• 1H-Pyrazole 100%
• Thiophene 100%
• Cell Viability 50%
• High Throughput Screening 50%
• Chemical Library 50%
• Acridine 50%
• Combinatorial Library 50%
• RNA Polymerase 50%

Pharmacology, Toxicology and Pharmaceutical Science

• West Nile Virus 100%
• Pyrazoline 57%
• Pyrazole 28%
• Thiophene 28%
• Infection 14%
• Structure Activity Relationship 14%
• Antiviral Drug 14%
• High-Throughput Screening 14%
• Yellow Fever 14%
• Flavivirus 14%
• Therapeutic Window 14%
• Dengue 14%
• RNA Polymerase 14%
• Virus RNA 14%
• RNA Helicase 14%
• Quinoline Derivative 14%
• Cell Viability 14%
• Cytotoxicity Assay 14%
• Combinatorial Library 14%
• Acridine Derivative 14%