Identification of intraocular lens materials using confocal Raman spectroscopy

Eefke E. Smit, Roel J. Erckens, Fred Hendrikse, Massoud Motamedi, James P. Wicksted, Wayne F. March

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Purpose: To develop and test a noninvasive method to identify intraocular lens (IOL) materials in vitro. Setting: Center for Biomedical Engineering and the Department of Ophthalmology University of Texas Medical Branch, Galveston, Texas, USA. Methods: A laser confocal Raman spectroscopy system (Conforam) was used for the noninvasive assessment of Raman spectra in the lower and the higher spectral regions (299.1 to 1833.7 cm-1 and 2633.8 to 3819.6 cm-1, respectively) of 4 IOL materials: silicone, poly(methyl methacrylate) (PMMA), acrylic, and hydrogel. Results: Each lens material showed a distinctive spectrum in both the higher and the lower spectral regions. Most materials had unique peaks and a distinct profile using 1 mW of laser power and a 1 second exposure time. All materials still had a unique spectrum n both the higher and the lower region that allowed 1 material to be distinguished from the others. Conclusions: A Conforam differentiated silicone, PMMA, acrylic, and hydrogel lenses in vitro. Raman spectroscopy using the Conforam may provide a fast, safe, and reliable noninvasive method to gain information about the material of an implanted IOL and the stability of lens materials and their coatings.

Original languageEnglish (US)
Pages (from-to)1498-1504
Number of pages7
JournalJournal of Cataract and Refractive Surgery
Volume25
Issue number11
DOIs
StatePublished - 1999

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Raman Spectrum Analysis
Intraocular Lenses
Lenses
Hydrogel
Polymethyl Methacrylate
Silicones
Lasers
Biomedical Engineering
Ophthalmology
In Vitro Techniques

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Identification of intraocular lens materials using confocal Raman spectroscopy. / Smit, Eefke E.; Erckens, Roel J.; Hendrikse, Fred; Motamedi, Massoud; Wicksted, James P.; March, Wayne F.

In: Journal of Cataract and Refractive Surgery, Vol. 25, No. 11, 1999, p. 1498-1504.

Research output: Contribution to journalArticle

Smit, Eefke E. ; Erckens, Roel J. ; Hendrikse, Fred ; Motamedi, Massoud ; Wicksted, James P. ; March, Wayne F. / Identification of intraocular lens materials using confocal Raman spectroscopy. In: Journal of Cataract and Refractive Surgery. 1999 ; Vol. 25, No. 11. pp. 1498-1504.
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AU - Smit, Eefke E.

AU - Erckens, Roel J.

AU - Hendrikse, Fred

AU - Motamedi, Massoud

AU - Wicksted, James P.

AU - March, Wayne F.

PY - 1999

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