Abstract
Purpose: To develop and test a noninvasive method to identify intraocular lens (IOL) materials in vitro. Setting: Center for Biomedical Engineering and the Department of Ophthalmology University of Texas Medical Branch, Galveston, Texas, USA. Methods: A laser confocal Raman spectroscopy system (Conforam) was used for the noninvasive assessment of Raman spectra in the lower and the higher spectral regions (299.1 to 1833.7 cm-1 and 2633.8 to 3819.6 cm-1, respectively) of 4 IOL materials: silicone, poly(methyl methacrylate) (PMMA), acrylic, and hydrogel. Results: Each lens material showed a distinctive spectrum in both the higher and the lower spectral regions. Most materials had unique peaks and a distinct profile using 1 mW of laser power and a 1 second exposure time. All materials still had a unique spectrum n both the higher and the lower region that allowed 1 material to be distinguished from the others. Conclusions: A Conforam differentiated silicone, PMMA, acrylic, and hydrogel lenses in vitro. Raman spectroscopy using the Conforam may provide a fast, safe, and reliable noninvasive method to gain information about the material of an implanted IOL and the stability of lens materials and their coatings.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1498-1504 |
| Number of pages | 7 |
| Journal | Journal of Cataract and Refractive Surgery |
| Volume | 25 |
| Issue number | 11 |
| DOIs | |
| State | Published - 1999 |
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ASJC Scopus subject areas
- Ophthalmology
Cite this
Identification of intraocular lens materials using confocal Raman spectroscopy. / Smit, Eefke E.; Erckens, Roel J.; Hendrikse, Fred; Motamedi, Massoud; Wicksted, James P.; March, Wayne F.
In: Journal of Cataract and Refractive Surgery, Vol. 25, No. 11, 1999, p. 1498-1504.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Identification of intraocular lens materials using confocal Raman spectroscopy
AU - Smit, Eefke E.
AU - Erckens, Roel J.
AU - Hendrikse, Fred
AU - Motamedi, Massoud
AU - Wicksted, James P.
AU - March, Wayne F.
PY - 1999
Y1 - 1999
N2 - Purpose: To develop and test a noninvasive method to identify intraocular lens (IOL) materials in vitro. Setting: Center for Biomedical Engineering and the Department of Ophthalmology University of Texas Medical Branch, Galveston, Texas, USA. Methods: A laser confocal Raman spectroscopy system (Conforam) was used for the noninvasive assessment of Raman spectra in the lower and the higher spectral regions (299.1 to 1833.7 cm-1 and 2633.8 to 3819.6 cm-1, respectively) of 4 IOL materials: silicone, poly(methyl methacrylate) (PMMA), acrylic, and hydrogel. Results: Each lens material showed a distinctive spectrum in both the higher and the lower spectral regions. Most materials had unique peaks and a distinct profile using 1 mW of laser power and a 1 second exposure time. All materials still had a unique spectrum n both the higher and the lower region that allowed 1 material to be distinguished from the others. Conclusions: A Conforam differentiated silicone, PMMA, acrylic, and hydrogel lenses in vitro. Raman spectroscopy using the Conforam may provide a fast, safe, and reliable noninvasive method to gain information about the material of an implanted IOL and the stability of lens materials and their coatings.
AB - Purpose: To develop and test a noninvasive method to identify intraocular lens (IOL) materials in vitro. Setting: Center for Biomedical Engineering and the Department of Ophthalmology University of Texas Medical Branch, Galveston, Texas, USA. Methods: A laser confocal Raman spectroscopy system (Conforam) was used for the noninvasive assessment of Raman spectra in the lower and the higher spectral regions (299.1 to 1833.7 cm-1 and 2633.8 to 3819.6 cm-1, respectively) of 4 IOL materials: silicone, poly(methyl methacrylate) (PMMA), acrylic, and hydrogel. Results: Each lens material showed a distinctive spectrum in both the higher and the lower spectral regions. Most materials had unique peaks and a distinct profile using 1 mW of laser power and a 1 second exposure time. All materials still had a unique spectrum n both the higher and the lower region that allowed 1 material to be distinguished from the others. Conclusions: A Conforam differentiated silicone, PMMA, acrylic, and hydrogel lenses in vitro. Raman spectroscopy using the Conforam may provide a fast, safe, and reliable noninvasive method to gain information about the material of an implanted IOL and the stability of lens materials and their coatings.
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U2 - 10.1016/S0886-3350(99)00239-4
DO - 10.1016/S0886-3350(99)00239-4
M3 - Article
C2 - 10569165
AN - SCOPUS:0032738020
VL - 25
SP - 1498
EP - 1504
JO - Journal of Cataract and Refractive Surgery
JF - Journal of Cataract and Refractive Surgery
SN - 0886-3350
IS - 11
ER -