Abstract
The mouse c-mos proto-oncogene RNA is expressed primarily in mouse gonadal tissues and embryos. Until now, the c-mos protein has not been identified. Utilizing two different site-directed affinity purified anti-peptide anti-bodies, we have identified a 43 kDa c-mos protein in mouse testes and in germ cell preparations derived from testes. This 43 kDa testicular protein was found to be structurally related to a bacterially expressed c-mos protein by peptide mapping. Immunoblots of whole mouse sections were employed to establishe that the c-mos protein is expressed primarily in the testes.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 225-229 |
| Number of pages | 5 |
| Journal | Oncogene |
| Volume | 3 |
| Issue number | 2 |
| State | Published - 1988 |
| Externally published | Yes |
ASJC Scopus subject areas
- Molecular Biology
- Genetics
- Cancer Research