The mouse c-mos proto-oncogene RNA is expressed primarily in mouse gonadal tissues and embryos. Until now, the c-mos protein has not been identified. Utilizing two different site-directed affinity purified anti-peptide anti-bodies, we have identified a 43 kDa c-mos protein in mouse testes and in germ cell preparations derived from testes. This 43 kDa testicular protein was found to be structurally related to a bacterially expressed c-mos protein by peptide mapping. Immunoblots of whole mouse sections were employed to establishe that the c-mos protein is expressed primarily in the testes.
|Original language||English (US)|
|Number of pages||5|
|State||Published - Jan 1 1988|
ASJC Scopus subject areas
- Molecular Biology
- Cancer Research