Abstract
Pure red cell aplasia (PRCA) is characterized by near absence of red blood cell precursors in the bone marrow with associated anemia and reticulocytopenia. Megakaryocytes and white blood cell precursors remain intact. Acute self-limited PRCA is the most common form. Acquired chronic PRCA is often idiopathic but can be associated with underlying disorders such as thymoma or autoimmune diseases. Congenital PRCA is associated with physical abnormalities. Pure red blood cell aplasia should always be included in the differential diagnosis of chronic unexplained anemia. We report a case of idiopathic pure red blood cell aplasia in an elderly male who has had a chronic anemia with recurrent blood transfusions for about 30 years.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 501-505 |
| Number of pages | 5 |
| Journal | South Dakota journal of medicine. |
| Volume | 58 |
| Issue number | 12 |
| State | Published - Dec 2005 |
| Externally published | Yes |
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Idiopathic pure red cell aplasia : case report with review of literature. / Khalife, Wissam; Murunga, Eric; Mahmoud, Fade.
In: South Dakota journal of medicine., Vol. 58, No. 12, 12.2005, p. 501-505.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Idiopathic pure red cell aplasia
T2 - case report with review of literature.
AU - Khalife, Wissam
AU - Murunga, Eric
AU - Mahmoud, Fade
PY - 2005/12
Y1 - 2005/12
N2 - Pure red cell aplasia (PRCA) is characterized by near absence of red blood cell precursors in the bone marrow with associated anemia and reticulocytopenia. Megakaryocytes and white blood cell precursors remain intact. Acute self-limited PRCA is the most common form. Acquired chronic PRCA is often idiopathic but can be associated with underlying disorders such as thymoma or autoimmune diseases. Congenital PRCA is associated with physical abnormalities. Pure red blood cell aplasia should always be included in the differential diagnosis of chronic unexplained anemia. We report a case of idiopathic pure red blood cell aplasia in an elderly male who has had a chronic anemia with recurrent blood transfusions for about 30 years.
AB - Pure red cell aplasia (PRCA) is characterized by near absence of red blood cell precursors in the bone marrow with associated anemia and reticulocytopenia. Megakaryocytes and white blood cell precursors remain intact. Acute self-limited PRCA is the most common form. Acquired chronic PRCA is often idiopathic but can be associated with underlying disorders such as thymoma or autoimmune diseases. Congenital PRCA is associated with physical abnormalities. Pure red blood cell aplasia should always be included in the differential diagnosis of chronic unexplained anemia. We report a case of idiopathic pure red blood cell aplasia in an elderly male who has had a chronic anemia with recurrent blood transfusions for about 30 years.
UR - http://www.scopus.com/inward/record.url?scp=33746003290&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33746003290&partnerID=8YFLogxK
M3 - Article
VL - 58
SP - 501
EP - 505
JO - South Dakota journal of medicine
JF - South Dakota journal of medicine
SN - 0038-3317
IS - 12
ER -