IgM responses in chicken serum to live and inactivated infectious bronchitis virus vaccines.

N. R. Martins, A. P. Mockett, Alan Barrett, J. K. Cook

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Intramuscular (i.m.) administration of infectious bronchitis virus (IBV) oil-emulsion vaccine (OEV) to IBV-primed or unprimed chickens resulted in the production of zero or minimal concentrations of IBV-specific IgM in the serum, as measured by enzyme-linked immunosorbent assay of gel chromatography fractions. Live-attenuated infectious bronchitis (IB) vaccine given i.m. or by eyedrop stimulated the production of IBV-specific IgM in similar amounts following inoculation by both routes. These levels were comparable to those found in earlier studies following intranasal inoculation with a virulent strain of IBV and confirm that the detection of IBV-specific IgM is a valuable aid to the diagnosis of recent infection. As expected, administration of live-attenuated IB vaccines i.m. or by eyedrop protected the respiratory tract against challenge with virulent virus 24 days later; however, OEV given i.m. did not.

Original languageEnglish (US)
Pages (from-to)470-475
Number of pages6
JournalAvian Diseases
Volume35
Issue number3
StatePublished - Jul 1991
Externally publishedYes

Fingerprint

Infectious bronchitis virus
Immunoglobulin M
Chickens
Vaccines
vaccines
chickens
Serum
infectious bronchitis
Bronchitis
Ophthalmic Solutions
Emulsions
emulsions
Oils
vaccination
oils
poultry production
intramuscular injection
respiratory system
Respiratory System
Gel Chromatography

ASJC Scopus subject areas

  • Cancer Research
  • Immunology
  • veterinary(all)

Cite this

IgM responses in chicken serum to live and inactivated infectious bronchitis virus vaccines. / Martins, N. R.; Mockett, A. P.; Barrett, Alan; Cook, J. K.

In: Avian Diseases, Vol. 35, No. 3, 07.1991, p. 470-475.

Research output: Contribution to journalArticle

Martins, N. R. ; Mockett, A. P. ; Barrett, Alan ; Cook, J. K. / IgM responses in chicken serum to live and inactivated infectious bronchitis virus vaccines. In: Avian Diseases. 1991 ; Vol. 35, No. 3. pp. 470-475.
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