Immigration and major affective disorder

W. Grove, P. J. Clayton, J. Endicott, R. M.A. Hirschfeld, N. C. Andreasen, G. L. Klerman

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


We studied bipolar (ever manic; n: = 297) primary unipolar (never secondary; n: = 328), and secondary unipolar (n: = 241) RDC major affective disorder patients in the NIMH — CRB Collaborative Study of the Psychobiology of Depression — Clinical. We examined rates of immigration, for patients and their parents, in these three diagnostic groups. Primary patients had a twofold increase in the odds in favor of immigration, compared to secondary patients. The difference persisted when proband age was statistically controlled, and could not be accounted for by any difference in sex ratios between groups. Previous findings of an increased rate of immigration in bipolar patients could not be replicated.

Original languageEnglish (US)
Pages (from-to)548-552
Number of pages5
JournalActa Psychiatrica Scandinavica
Issue number6
StatePublished - Dec 1986
Externally publishedYes


  • Immigration
  • primary depression: secondary depression

ASJC Scopus subject areas

  • Psychiatry and Mental health


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