Estado imune contra o virus vacinal (17D) da febre amarela em duas populacoes do Estado da Bahia

Translated title of the contribution: Immunity against yellow fever vaccinal virus (17D) in two population of the Bahia State, Brazil

S. Santos-Torres, A. Straatmann, K. Mota, P. F.C. Vasconcelos, A. P.A. Travassos da Rosa, J. Tavares-Neto

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

The occurrence of cases of yellow fever (YF) and also the extensive distribution of A. aegypti in Brazil, inspired a study about the estimate of immunity against vacinal virus (17D) among the residents at two cities of the Bahia state, Ipupiara (n = 461) and Prado (n = 228). At this non-endemic area of YF, the search for serology antibody against 17D (Ab17D) and 18 another arbovirus was made thereby hemagglutination inhibition (HI). Only 1.2% (8/689) showed Ab17D, six of those with monotypic sort. The heterotypic sort for flavivirus (FLV) was interpreted as associated to immunity against 17D too, being much frequent in Prado (30.3%) than in Ipupiara (23.2%). The age ≥50 years and residence in another states were related to seropositive for FLV, the same way that vaccination's history (17D). However, the history of vaccination presented low percentages of sensibility (≤ 45.4%) and predictive-positive value (£38.4%), but high specificity (≥70.8%) and predictive-negative value (≥78.8%). Therefore, the frequency of residents with Ab17D was low (1.2%), although the higher frequency (25.5%) of antibody FLV carrier's, what signifies that 26.7% of the studied population should present protection against the YF virus.

Original languagePortuguese
Pages (from-to)39-46
Number of pages8
JournalRevista da Sociedade Brasileira de Medicina Tropical
Volume33
Issue number1
StatePublished - May 9 2000

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Keywords

  • Bahia State
  • Seroprevalence
  • Vaccine 17D
  • Yellow fever

ASJC Scopus subject areas

  • Parasitology
  • Microbiology (medical)
  • Infectious Diseases

Cite this

Santos-Torres, S., Straatmann, A., Mota, K., Vasconcelos, P. F. C., Travassos da Rosa, A. P. A., & Tavares-Neto, J. (2000). Estado imune contra o virus vacinal (17D) da febre amarela em duas populacoes do Estado da Bahia. Revista da Sociedade Brasileira de Medicina Tropical, 33(1), 39-46.