Immuno- and gene-therapeutic strategies targeted against cancer (mainly focusing on pancreatic cancer)

Kiyoshi Yoshimura, Kelly Olino, Barish H. Edil, Richard D. Schulick, Masaaki Oka

Research output: Contribution to journalReview article

2 Scopus citations

Abstract

Current treatment modalities of surgical resection and chemotherapy against cancers have improved survival. However, mortality from tumor recurrence remains high. Immunotherapy and gene therapy are potential additions to the treatment arsenal in the care of cancer patients. These novel therapeutic approaches need further investigation in in vitro and in vivo models as they are developed for potential use in humans. Here we reviewed immunotherapies and gene therapies that included clinical trials against cancers (mainly focusing on pancreatic cancer) suggesting the strong possibility of using these novel approaches.

Original languageEnglish (US)
Pages (from-to)404-410
Number of pages7
JournalSurgery Today
Volume40
Issue number5
DOIs
StatePublished - May 1 2010

Keywords

  • Gastrointestinal cancer
  • Immunotherapy

ASJC Scopus subject areas

  • Surgery

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