Immunohistochemical study of the phrenic ganglion

R. Shane Tubbs, William Stetler, David R. Kelly, Danitra Blevins, Robert Lott, Rita Humphrey, Mohammadali Mohajel Shoja, Marios Loukas

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Peripheral nerve 'pseudoganglia' are described in the literature with little focus on histology. The phrenic ganglia, which are located on the inferior surface of the diaphragm and are associated with the phrenic nerves, have been described by some authors as potentially sympathetic ganglia although this, to the authors'knowledge, has not been proven. The purpose of the present study was to elucidate further the true autonomic nature of this collection of nerve cell bodies. In eight fresh adult cadavers <6 h after death, the left and right phrenic ganglia were harvested and subjected to immunochemistry. All phrenic ganglia were vasoactive intestinal polypeptide negative but tyrosine hydroxylase positive. These findings indicate that the phrenic ganglia are sympathetic ganglia with most likely a vasomotor function.

Original languageEnglish (US)
Pages (from-to)159-161
Number of pages3
JournalAnatomical Science International
Volume83
Issue number3
DOIs
StatePublished - Sep 1 2008
Externally publishedYes

Fingerprint

Diaphragm
Ganglia
Sympathetic Ganglia
Immunochemistry
Phrenic Nerve
Vasoactive Intestinal Peptide
Tyrosine 3-Monooxygenase
Peripheral Nerves
Cadaver
Histology
Neurons

Keywords

  • Anatomy
  • Diaphragm
  • Pseudoganglion

ASJC Scopus subject areas

  • Anatomy

Cite this

Tubbs, R. S., Stetler, W., Kelly, D. R., Blevins, D., Lott, R., Humphrey, R., ... Loukas, M. (2008). Immunohistochemical study of the phrenic ganglion. Anatomical Science International, 83(3), 159-161. https://doi.org/10.1111/j.1447-073X.2007.00224.x

Immunohistochemical study of the phrenic ganglion. / Tubbs, R. Shane; Stetler, William; Kelly, David R.; Blevins, Danitra; Lott, Robert; Humphrey, Rita; Mohajel Shoja, Mohammadali; Loukas, Marios.

In: Anatomical Science International, Vol. 83, No. 3, 01.09.2008, p. 159-161.

Research output: Contribution to journalArticle

Tubbs, RS, Stetler, W, Kelly, DR, Blevins, D, Lott, R, Humphrey, R, Mohajel Shoja, M & Loukas, M 2008, 'Immunohistochemical study of the phrenic ganglion', Anatomical Science International, vol. 83, no. 3, pp. 159-161. https://doi.org/10.1111/j.1447-073X.2007.00224.x
Tubbs RS, Stetler W, Kelly DR, Blevins D, Lott R, Humphrey R et al. Immunohistochemical study of the phrenic ganglion. Anatomical Science International. 2008 Sep 1;83(3):159-161. https://doi.org/10.1111/j.1447-073X.2007.00224.x
Tubbs, R. Shane ; Stetler, William ; Kelly, David R. ; Blevins, Danitra ; Lott, Robert ; Humphrey, Rita ; Mohajel Shoja, Mohammadali ; Loukas, Marios. / Immunohistochemical study of the phrenic ganglion. In: Anatomical Science International. 2008 ; Vol. 83, No. 3. pp. 159-161.
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