Imported malaria in pregnancy: Report of four cases and review of management

Durgaprasad Subramanian, Kenneth J. Moise, A. Clinton White

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Malaria is a common infection worldwide. Increased travel by pregnant women makes it likely that physicians in the United States will see cases of malaria in this population. We observed four cases of malaria during pregnancy over an 8-month period at a general hospital in the United States. These cases illustrate the association between pregnancy and severe malaria in the mother and congenital infection in the newborn. We also noted delays in diagnosis because malaria was mistaken for other common illnesses. Therapy was complicated by concerns about the safety of antimalarial agents for the fetus and newborn as well as drug resistance. While chloroquine is safe for use in pregnancy, drug resistance is now common, especially when the etiologic organism is Plasmodiumfalciparum. There are concerns about the safety of administering other antimalarial agents during pregnancy (e.g., mefloquine). Concerns about the safety and availability of these agents limit options for prophylaxis.

Original languageEnglish (US)
Pages (from-to)408-413
Number of pages6
JournalClinical Infectious Diseases
Volume15
Issue number3
StatePublished - Sep 1992
Externally publishedYes

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Case Management
Malaria
Pregnancy
Antimalarials
Safety
Drug Resistance
Newborn Infant
Mefloquine
Chloroquine
Infection
General Hospitals
Pregnant Women
Fetus
Mothers
Physicians
Population

ASJC Scopus subject areas

  • Immunology

Cite this

Imported malaria in pregnancy : Report of four cases and review of management. / Subramanian, Durgaprasad; Moise, Kenneth J.; White, A. Clinton.

In: Clinical Infectious Diseases, Vol. 15, No. 3, 09.1992, p. 408-413.

Research output: Contribution to journalArticle

Subramanian, Durgaprasad ; Moise, Kenneth J. ; White, A. Clinton. / Imported malaria in pregnancy : Report of four cases and review of management. In: Clinical Infectious Diseases. 1992 ; Vol. 15, No. 3. pp. 408-413.
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