Improvement of venous leg ulcers with androgen replacement therapy in a patient with undiagnosed klinefelter syndrome

Shwetha Thukuntla, Pratima Kumar

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Klinefelter syndrome (Ks) is the most common genetic form of male hypogonadism. The majority (80-90%) of patients have 47, XXY karyotype while mosaicism is seen in only 10-20% of patients. Leg ulcers may be a presenting symptom of KS with a prevalence of 6-13%. Treatment with testosterone has been reported to improve the ulcers.

Original languageEnglish (US)
Pages (from-to)233-234
Number of pages2
JournalDermato-Endocrinology
Volume3
Issue number4
DOIs
StatePublished - Oct 2011

Keywords

  • Androgen therapy
  • Klinefelter syndrome
  • Leg ulcers
  • Mosaicism
  • Plasminogen activator inhibitor

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Dermatology

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