Inactivation of PNKP by Mutant ATXN3 Triggers Apoptosis by Activating the DNA Damage-Response Pathway in SCA3

Rui Gao, Yongping Liu, Anabela Silva-Fernandes, Xiang Fang, Adriana Paulucci-Holthauzen, Arpita Chatterjee, Hang L. Zhang, Tohru Matsuura, Sanjeev Choudhary, Tetsuo Ashizawa, Arnulf H. Koeppen, Patricia Maciel, Tapas K. Hazra, Partha S. Sarkar

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Biochemistry, Genetics and Molecular Biology

Neuroscience

Pharmacology, Toxicology and Pharmaceutical Science