Abstract
The Texas Department of Criminal Justice (TDCJ) houses many subjects with acquired immunodeficiency syndrome (AIDS) who receive medical care in a comprehensive AIDS treatment center. In this case-control autopsy survey, we compared pathological outcomes of TDCJ inmates treated at the center (n = 155) with nonincarcerated patients who died during the same period (n = 155). Using multiple regression analysis and a proportional hazards model, survival time in the prisoners was equivalent to that in the controls. With few exceptions, the prevalences of opportunistic viral, fungal, protozoal, and bacterial infections contributing to mortality were equivalent between groups. Mycobacterium tuberculosis was isolated more frequently in the inmates, and M avium intracellulare was isolated less frequently (P<0001). The inmates had a higher prevalence of bacterial infection of the central nervous system (CNS) (9.1% v 1.4%; P < .006); half of all CNS bacterial infections were caused by M tuberculosis. Inmates had significantly lower prevalences of vacuolar myelopathy (P < .006) and severe wasting disease (P < .0009). We conclude that survival of prison inmates with AIDS treated in a comprehensive AIDS treatment center was equivalent to that of nonincarcerated subjects with AIDS. Prevalences of certain complications of AIDS differed in the inmates, showing that the prison environment influenced some of the underlying causes of AIDS morbidity and mortality.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1282-1289 |
| Number of pages | 8 |
| Journal | Human Pathology |
| Volume | 27 |
| Issue number | 12 |
| DOIs | |
| State | Published - 1996 |
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Keywords
- AIDS
- cachexia
- incarceration
- meningitis
- mycobacterium
- prison
- tuberculosis
- vacuolar myelopathy
ASJC Scopus subject areas
- Pathology and Forensic Medicine
Cite this
Incarceration and the acquired immunodeficiency syndrome : Autopsy results in Texas prison inmates. / Gelman, Benjamin; Wolf, Dwayne A.; Olano, Juan; Linthicum, Lannette C.
In: Human Pathology, Vol. 27, No. 12, 1996, p. 1282-1289.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Incarceration and the acquired immunodeficiency syndrome
T2 - Autopsy results in Texas prison inmates
AU - Gelman, Benjamin
AU - Wolf, Dwayne A.
AU - Olano, Juan
AU - Linthicum, Lannette C.
PY - 1996
Y1 - 1996
N2 - The Texas Department of Criminal Justice (TDCJ) houses many subjects with acquired immunodeficiency syndrome (AIDS) who receive medical care in a comprehensive AIDS treatment center. In this case-control autopsy survey, we compared pathological outcomes of TDCJ inmates treated at the center (n = 155) with nonincarcerated patients who died during the same period (n = 155). Using multiple regression analysis and a proportional hazards model, survival time in the prisoners was equivalent to that in the controls. With few exceptions, the prevalences of opportunistic viral, fungal, protozoal, and bacterial infections contributing to mortality were equivalent between groups. Mycobacterium tuberculosis was isolated more frequently in the inmates, and M avium intracellulare was isolated less frequently (P<0001). The inmates had a higher prevalence of bacterial infection of the central nervous system (CNS) (9.1% v 1.4%; P < .006); half of all CNS bacterial infections were caused by M tuberculosis. Inmates had significantly lower prevalences of vacuolar myelopathy (P < .006) and severe wasting disease (P < .0009). We conclude that survival of prison inmates with AIDS treated in a comprehensive AIDS treatment center was equivalent to that of nonincarcerated subjects with AIDS. Prevalences of certain complications of AIDS differed in the inmates, showing that the prison environment influenced some of the underlying causes of AIDS morbidity and mortality.
AB - The Texas Department of Criminal Justice (TDCJ) houses many subjects with acquired immunodeficiency syndrome (AIDS) who receive medical care in a comprehensive AIDS treatment center. In this case-control autopsy survey, we compared pathological outcomes of TDCJ inmates treated at the center (n = 155) with nonincarcerated patients who died during the same period (n = 155). Using multiple regression analysis and a proportional hazards model, survival time in the prisoners was equivalent to that in the controls. With few exceptions, the prevalences of opportunistic viral, fungal, protozoal, and bacterial infections contributing to mortality were equivalent between groups. Mycobacterium tuberculosis was isolated more frequently in the inmates, and M avium intracellulare was isolated less frequently (P<0001). The inmates had a higher prevalence of bacterial infection of the central nervous system (CNS) (9.1% v 1.4%; P < .006); half of all CNS bacterial infections were caused by M tuberculosis. Inmates had significantly lower prevalences of vacuolar myelopathy (P < .006) and severe wasting disease (P < .0009). We conclude that survival of prison inmates with AIDS treated in a comprehensive AIDS treatment center was equivalent to that of nonincarcerated subjects with AIDS. Prevalences of certain complications of AIDS differed in the inmates, showing that the prison environment influenced some of the underlying causes of AIDS morbidity and mortality.
KW - AIDS
KW - cachexia
KW - incarceration
KW - meningitis
KW - mycobacterium
KW - prison
KW - tuberculosis
KW - vacuolar myelopathy
UR - http://www.scopus.com/inward/record.url?scp=0029807568&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029807568&partnerID=8YFLogxK
U2 - 10.1016/S0046-8177(96)90338-X
DO - 10.1016/S0046-8177(96)90338-X
M3 - Article
VL - 27
SP - 1282
EP - 1289
JO - Human Pathology
JF - Human Pathology
SN - 0046-8177
IS - 12
ER -