Incidental Diagnosis of Metastatic Breast Cancer in a Man with 99mTc-PSMA SPECT/CT

César D. Zárate-García; David R. Cardoza-Ochoa; Yazmín Sánchez-Vera; Jorge Iván González-Díaz

doi:10.1097/RLU.0000000000004549

Incidental Diagnosis of Metastatic Breast Cancer in a Man with ^99mTc-PSMA SPECT/CT

César D. Zárate-García, David R. Cardoza-Ochoa, Yazmín Sánchez-Vera, Jorge Iván González-Díaz

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Breast cancer in men is a rare and unsuspected malignancy. A 48-year-old man begins with disabling low back pain. The CT scan reported a compression fracture in L2 and diffuse skeletal lesions suggestive of metastatic disease. The serum prostate-specific antigen was 6.2 ng/mL. He was referred for SPECT/CT with 99mTc-EDDA/HYNIC-inhibitor prostate-specific membrane antigen due to clinical suspicion of prostate cancer. SPECT/CT with 99mTc-EDDA/HYNIC-inhibitor prostate-specific membrane antigen showed a primary lesion in the left breast and multiple bone lesions. Biopsy confirmed infiltrating ductal carcinoma with positive hormone receptors and indeterminate HER2 (human epidermal growth factor receptor 2).

Original language	English (US)
Pages (from-to)	E163-E164
Journal	Clinical Nuclear Medicine
Volume	48
Issue number	4
DOIs	https://doi.org/10.1097/RLU.0000000000004549
State	Published - Apr 1 2023
Externally published	Yes

Keywords

Tc-PSMA
incidental finding
male breast cancer
SPECT/CT

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Access to Document

10.1097/RLU.0000000000004549

Cite this

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title = "Incidental Diagnosis of Metastatic Breast Cancer in a Man with 99mTc-PSMA SPECT/CT",

abstract = "Breast cancer in men is a rare and unsuspected malignancy. A 48-year-old man begins with disabling low back pain. The CT scan reported a compression fracture in L2 and diffuse skeletal lesions suggestive of metastatic disease. The serum prostate-specific antigen was 6.2 ng/mL. He was referred for SPECT/CT with 99mTc-EDDA/HYNIC-inhibitor prostate-specific membrane antigen due to clinical suspicion of prostate cancer. SPECT/CT with 99mTc-EDDA/HYNIC-inhibitor prostate-specific membrane antigen showed a primary lesion in the left breast and multiple bone lesions. Biopsy confirmed infiltrating ductal carcinoma with positive hormone receptors and indeterminate HER2 (human epidermal growth factor receptor 2).",

keywords = "Tc-PSMA, incidental finding, male breast cancer, SPECT/CT",

author = "Z{\'a}rate-Garc{\'i}a, \{C{\'e}sar D.\} and Cardoza-Ochoa, \{David R.\} and Yazm{\'i}n S{\'a}nchez-Vera and Gonz{\'a}lez-D{\'i}az, \{Jorge Iv{\'a}n\}",

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T1 - Incidental Diagnosis of Metastatic Breast Cancer in a Man with 99mTc-PSMA SPECT/CT

AU - Zárate-García, César D.

AU - Cardoza-Ochoa, David R.

AU - Sánchez-Vera, Yazmín

AU - González-Díaz, Jorge Iván

PY - 2023/4/1

Y1 - 2023/4/1

N2 - Breast cancer in men is a rare and unsuspected malignancy. A 48-year-old man begins with disabling low back pain. The CT scan reported a compression fracture in L2 and diffuse skeletal lesions suggestive of metastatic disease. The serum prostate-specific antigen was 6.2 ng/mL. He was referred for SPECT/CT with 99mTc-EDDA/HYNIC-inhibitor prostate-specific membrane antigen due to clinical suspicion of prostate cancer. SPECT/CT with 99mTc-EDDA/HYNIC-inhibitor prostate-specific membrane antigen showed a primary lesion in the left breast and multiple bone lesions. Biopsy confirmed infiltrating ductal carcinoma with positive hormone receptors and indeterminate HER2 (human epidermal growth factor receptor 2).

AB - Breast cancer in men is a rare and unsuspected malignancy. A 48-year-old man begins with disabling low back pain. The CT scan reported a compression fracture in L2 and diffuse skeletal lesions suggestive of metastatic disease. The serum prostate-specific antigen was 6.2 ng/mL. He was referred for SPECT/CT with 99mTc-EDDA/HYNIC-inhibitor prostate-specific membrane antigen due to clinical suspicion of prostate cancer. SPECT/CT with 99mTc-EDDA/HYNIC-inhibitor prostate-specific membrane antigen showed a primary lesion in the left breast and multiple bone lesions. Biopsy confirmed infiltrating ductal carcinoma with positive hormone receptors and indeterminate HER2 (human epidermal growth factor receptor 2).

KW - Tc-PSMA

KW - incidental finding

KW - male breast cancer

KW - SPECT/CT

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