Incidental GIST after appendectomy in a pediatric patient: A first instance and review of pediatric patients with CD117 confirmed GISTs

Sifrance Tran; Michael Dingeldein; Sarah C. Mengshol; Saundra Kay; Anthony C. Chin

doi:10.1007/s00383-013-3432-3

Incidental GIST after appendectomy in a pediatric patient: A first instance and review of pediatric patients with CD117 confirmed GISTs

Sifrance Tran, Michael Dingeldein, Sarah C. Mengshol, Saundra Kay, Anthony C. Chin

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

A 7-year-old boy underwent uncomplicated laparoscopic appendectomy for acute appendicitis. Incidentally, he was found to have a spindle cell tumor with CD117 immunopositivity, consistent with gastrointestinal stromal tumor (GIST) in the appendix. Although commonly reported in adults, pediatric GISTs are rare gastrointestinal malignancies that occur in only 1.4-2.7 % of children and adolescents [1]. Due to the paucity of reports, data are insufficient to adequately characterize tumor behavior, recurrence, and survival. We present the first case of pediatric GIST in the appendix. In addition, a review of the literature for CD117 confirmed pediatric GISTs was conducted to summarize its clinical features and current treatment options.

Original language	English (US)
Pages (from-to)	457-466
Number of pages	10
Journal	Pediatric Surgery International
Volume	30
Issue number	4
DOIs	https://doi.org/10.1007/s00383-013-3432-3
State	Published - Apr 2014
Externally published	Yes

Keywords

Appendicitis
CD117
GIST
Gastrointestinal
Pediatric
Stromal

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Surgery

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10.1007/s00383-013-3432-3

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title = "Incidental GIST after appendectomy in a pediatric patient: A first instance and review of pediatric patients with CD117 confirmed GISTs",

abstract = "A 7-year-old boy underwent uncomplicated laparoscopic appendectomy for acute appendicitis. Incidentally, he was found to have a spindle cell tumor with CD117 immunopositivity, consistent with gastrointestinal stromal tumor (GIST) in the appendix. Although commonly reported in adults, pediatric GISTs are rare gastrointestinal malignancies that occur in only 1.4-2.7 % of children and adolescents [1]. Due to the paucity of reports, data are insufficient to adequately characterize tumor behavior, recurrence, and survival. We present the first case of pediatric GIST in the appendix. In addition, a review of the literature for CD117 confirmed pediatric GISTs was conducted to summarize its clinical features and current treatment options.",

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AU - Dingeldein, Michael

AU - Mengshol, Sarah C.

AU - Kay, Saundra

AU - Chin, Anthony C.

PY - 2014/4

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N2 - A 7-year-old boy underwent uncomplicated laparoscopic appendectomy for acute appendicitis. Incidentally, he was found to have a spindle cell tumor with CD117 immunopositivity, consistent with gastrointestinal stromal tumor (GIST) in the appendix. Although commonly reported in adults, pediatric GISTs are rare gastrointestinal malignancies that occur in only 1.4-2.7 % of children and adolescents [1]. Due to the paucity of reports, data are insufficient to adequately characterize tumor behavior, recurrence, and survival. We present the first case of pediatric GIST in the appendix. In addition, a review of the literature for CD117 confirmed pediatric GISTs was conducted to summarize its clinical features and current treatment options.

AB - A 7-year-old boy underwent uncomplicated laparoscopic appendectomy for acute appendicitis. Incidentally, he was found to have a spindle cell tumor with CD117 immunopositivity, consistent with gastrointestinal stromal tumor (GIST) in the appendix. Although commonly reported in adults, pediatric GISTs are rare gastrointestinal malignancies that occur in only 1.4-2.7 % of children and adolescents [1]. Due to the paucity of reports, data are insufficient to adequately characterize tumor behavior, recurrence, and survival. We present the first case of pediatric GIST in the appendix. In addition, a review of the literature for CD117 confirmed pediatric GISTs was conducted to summarize its clinical features and current treatment options.

KW - Appendicitis

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KW - GIST

KW - Gastrointestinal

KW - Pediatric

KW - Stromal

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Incidental GIST after appendectomy in a pediatric patient: A first instance and review of pediatric patients with CD117 confirmed GISTs

Abstract

Keywords

ASJC Scopus subject areas

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