Incidental GIST after appendectomy in a pediatric patient: A first instance and review of pediatric patients with CD117 confirmed GISTs

Sifrance Tran, Michael Dingeldein, Sarah C. Mengshol, Saundra Kay, Anthony C. Chin

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

A 7-year-old boy underwent uncomplicated laparoscopic appendectomy for acute appendicitis. Incidentally, he was found to have a spindle cell tumor with CD117 immunopositivity, consistent with gastrointestinal stromal tumor (GIST) in the appendix. Although commonly reported in adults, pediatric GISTs are rare gastrointestinal malignancies that occur in only 1.4-2.7 % of children and adolescents [1]. Due to the paucity of reports, data are insufficient to adequately characterize tumor behavior, recurrence, and survival. We present the first case of pediatric GIST in the appendix. In addition, a review of the literature for CD117 confirmed pediatric GISTs was conducted to summarize its clinical features and current treatment options.

Original languageEnglish (US)
Pages (from-to)457-466
Number of pages10
JournalPediatric Surgery International
Volume30
Issue number4
DOIs
StatePublished - Apr 2014
Externally publishedYes

Keywords

  • Appendicitis
  • CD117
  • GIST
  • Gastrointestinal
  • Pediatric
  • Stromal

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery

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