Incontinentia pigmenti. Evidence for both neutrophil and lymphocyte dysfunction

R. T. Jessen, D. E. Van Epps, James Goodwin, J. Bowerman

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

A child with incontinentia pigmenti (Bloch-Sultzberger syndrome) had recurrent pneumococcal meningitis and pneumococcal bacteremia with associated subdural hematomas. Immunologic evaluation revealed defective neutrophil chemotaxis with normal neutrophil chemiluminescense. In addition, lymphocytes showed a depressed proliferative response to phytohemagglutinin stimulation. An immunologic defect may prove to be part of this syndrome.

Original languageEnglish (US)
Pages (from-to)1182-1186
Number of pages5
JournalArchives of Dermatology
Volume114
Issue number8
DOIs
StatePublished - 1978
Externally publishedYes

Fingerprint

Incontinentia Pigmenti
Pneumococcal Meningitis
Neutrophils
Lymphocytes
Subdural Hematoma
Phytohemagglutinins
Chemotaxis
Bacteremia

ASJC Scopus subject areas

  • Dermatology

Cite this

Incontinentia pigmenti. Evidence for both neutrophil and lymphocyte dysfunction. / Jessen, R. T.; Van Epps, D. E.; Goodwin, James; Bowerman, J.

In: Archives of Dermatology, Vol. 114, No. 8, 1978, p. 1182-1186.

Research output: Contribution to journalArticle

Jessen, R. T. ; Van Epps, D. E. ; Goodwin, James ; Bowerman, J. / Incontinentia pigmenti. Evidence for both neutrophil and lymphocyte dysfunction. In: Archives of Dermatology. 1978 ; Vol. 114, No. 8. pp. 1182-1186.
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