Incontinentia pigmenti. Evidence for both neutrophil and lymphocyte dysfunction

R. T. Jessen, D. E. Van Epps, James Goodwin, J. Bowerman

Research output: Contribution to journalArticle

27 Scopus citations


A child with incontinentia pigmenti (Bloch-Sultzberger syndrome) had recurrent pneumococcal meningitis and pneumococcal bacteremia with associated subdural hematomas. Immunologic evaluation revealed defective neutrophil chemotaxis with normal neutrophil chemiluminescense. In addition, lymphocytes showed a depressed proliferative response to phytohemagglutinin stimulation. An immunologic defect may prove to be part of this syndrome.

Original languageEnglish (US)
Pages (from-to)1182-1186
Number of pages5
JournalArchives of Dermatology
Issue number8
StatePublished - 1978
Externally publishedYes


ASJC Scopus subject areas

  • Dermatology

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