Incontinentia Pigmenti: Evidence for Both Neutrophil and Lymphocyte Dysfunction

R. Thomas Jessen, Dennis E. Van Epps, James S. Goodwin, James Bowerman

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

A child with incontinentia pigmenti (Bloch-Sultzberger syndrome) had recurrent pneumococcal meningitis and pneumococcal bacteremia with associated subdural hematomas. Immunologic evaluation revealed defective neutrophil chemotaxis with normal neutrophil chemiluminescense. In addition, lymphocytes showed a depressed proliferative response to phytohemagglutinin stimulation. An immunologic defect may prove to be part of this syndrome.

Original languageEnglish (US)
Pages (from-to)1182-1186
Number of pages5
JournalArchives of dermatology
Volume114
Issue number8
DOIs
StatePublished - Aug 1978
Externally publishedYes

ASJC Scopus subject areas

  • Dermatology

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