Increased efficiency of folding and peptide loading of mutant MHC class I molecules

Keyphrases

• MHC Class II 100%
• Efficiency Increase 100%
• HLA-A2 100%
• Peptide Loading 100%
• Endoplasmic Reticulum 40%
• Stable Conformation 40%
• Cell Surface 20%
• Binding Site 20%
• Mutant Protein 20%
• Major Histocompatibility Complex 20%
• Accessory Protein 20%
• β2-microglobulin (β2-MG) 20%
• Calreticulin 20%
• Heavy Chain 20%
• Co-precipitated 20%
• Tapasin 20%
• Fast Assembly 20%
• Peptide-loading Complex 20%
• Complex Set 20%
• Class I Alleles 20%

Biochemistry, Genetics and Molecular Biology

• Wild Type 100%
• Allele 100%
• Conformation 100%
• Major Histocompatibility Complex 100%
• Binding Site 50%
• Mutant Protein 50%
• Maturation 50%
• Heavy Chain 50%
• Calreticulin 50%
• Microglobulin 50%
• Tapasin 50%

Immunology and Microbiology

• Major Histocompatibility Complex 100%
• Peptides 100%
• Wild Type 40%
• Allele 40%
• Conformation 40%
• Endoplasmic reticulum 40%
• Cell Surface 20%
• Binding Site 20%
• Maturation 20%
• Calreticulin 20%
• Heavy Chain 20%