Infection

Theodore Miclau; Andrew H. Schmidt; Joseph C. Wenke; Lawrence X. Webb; Janette M. Harro; Ranjani Prabhakara; Mark E. Shirtliff

doi:10.1097/BOT.0b013e3181eebf12

Infection

Theodore Miclau, Andrew H. Schmidt, Joseph C. Wenke, Lawrence X. Webb, Janette M. Harro, Ranjani Prabhakara, Mark E. Shirtliff

Research output: Contribution to journal › Review article › peer-review

25 Scopus citations

Abstract

Musculoskeletal infection is a clinical problem with significant direct healthcare costs. The prevalence of infection after closed, elective surgery is frequently estimated to be less than 2%, but in severe injuries, posttraumatic infection rates have been reported as 10% or greater. Although clinical infections are found outside the realm of medical devices, it is clear that the enormous increase of infections associated with the use of implants presents a major challenge worldwide. This review summarizes recent advances in the understanding, diagnosis, and treatment of musculoskeletal infections.

Original language	English (US)
Pages (from-to)	583-586
Number of pages	4
Journal	Journal of orthopaedic trauma
Volume	24
Issue number	9
DOIs	https://doi.org/10.1097/BOT.0b013e3181eebf12
State	Published - Sep 2010
Externally published	Yes

Keywords

bacteria
biofilm
biomaterial
musculoskeletal infection

ASJC Scopus subject areas

Surgery
Orthopedics and Sports Medicine

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10.1097/BOT.0b013e3181eebf12

Cite this

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title = "Infection",

abstract = "Musculoskeletal infection is a clinical problem with significant direct healthcare costs. The prevalence of infection after closed, elective surgery is frequently estimated to be less than 2%, but in severe injuries, posttraumatic infection rates have been reported as 10% or greater. Although clinical infections are found outside the realm of medical devices, it is clear that the enormous increase of infections associated with the use of implants presents a major challenge worldwide. This review summarizes recent advances in the understanding, diagnosis, and treatment of musculoskeletal infections.",

keywords = "bacteria, biofilm, biomaterial, musculoskeletal infection",

author = "Theodore Miclau and Schmidt, {Andrew H.} and Wenke, {Joseph C.} and Webb, {Lawrence X.} and Harro, {Janette M.} and Ranjani Prabhakara and Shirtliff, {Mark E.}",

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pages = "583--586",

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AU - Miclau, Theodore

AU - Schmidt, Andrew H.

AU - Wenke, Joseph C.

AU - Webb, Lawrence X.

AU - Harro, Janette M.

AU - Prabhakara, Ranjani

AU - Shirtliff, Mark E.

PY - 2010/9

Y1 - 2010/9

N2 - Musculoskeletal infection is a clinical problem with significant direct healthcare costs. The prevalence of infection after closed, elective surgery is frequently estimated to be less than 2%, but in severe injuries, posttraumatic infection rates have been reported as 10% or greater. Although clinical infections are found outside the realm of medical devices, it is clear that the enormous increase of infections associated with the use of implants presents a major challenge worldwide. This review summarizes recent advances in the understanding, diagnosis, and treatment of musculoskeletal infections.

AB - Musculoskeletal infection is a clinical problem with significant direct healthcare costs. The prevalence of infection after closed, elective surgery is frequently estimated to be less than 2%, but in severe injuries, posttraumatic infection rates have been reported as 10% or greater. Although clinical infections are found outside the realm of medical devices, it is clear that the enormous increase of infections associated with the use of implants presents a major challenge worldwide. This review summarizes recent advances in the understanding, diagnosis, and treatment of musculoskeletal infections.

KW - bacteria

KW - biofilm

KW - biomaterial

KW - musculoskeletal infection

UR - http://www.scopus.com/inward/record.url?scp=77956247803&partnerID=8YFLogxK

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AN - SCOPUS:77956247803

SN - 0890-5339

VL - 24

SP - 583

EP - 586

JO - Journal of orthopaedic trauma

JF - Journal of orthopaedic trauma

IS - 9

ER -

Infection

Abstract

Keywords

ASJC Scopus subject areas

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