Inflammation, Immunity, and Vaccines for Helicobacter pylori Infection

Alojz Ihan, Iryna Pinchuk, Ellen J. Beswick

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The immune response to Helicobacter pylori is a multifaceted group of mechanisms involving responses that are both protective and damaging to the host. The innate and the adaptive immune responses lead to damaging inflammatory responses, but these responses may fail, allowing for persistence of many infections. Thus, developing new therapeutics and effective vaccines against H. pylori has proven to be arduous. In this manuscript, we will examine the advances in knowledge made in the past year in understanding the host immune response to H. pylori and the progress toward developing a vaccine.

Original languageEnglish (US)
Pages (from-to)16-21
Number of pages6
JournalHelicobacter
Volume17
Issue numberSUPPL.1
DOIs
StatePublished - Sep 2012

Fingerprint

Helicobacter Infections
Helicobacter pylori
Immunity
Vaccines
Inflammation
Adaptive Immunity
Innate Immunity
Infection
Therapeutics

Keywords

  • Gastric cancer
  • Host response
  • Inflammation
  • Vaccines

ASJC Scopus subject areas

  • Gastroenterology
  • Infectious Diseases

Cite this

Inflammation, Immunity, and Vaccines for Helicobacter pylori Infection. / Ihan, Alojz; Pinchuk, Iryna; Beswick, Ellen J.

In: Helicobacter, Vol. 17, No. SUPPL.1, 09.2012, p. 16-21.

Research output: Contribution to journalArticle

Ihan, Alojz ; Pinchuk, Iryna ; Beswick, Ellen J. / Inflammation, Immunity, and Vaccines for Helicobacter pylori Infection. In: Helicobacter. 2012 ; Vol. 17, No. SUPPL.1. pp. 16-21.
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