Toxic megacolon is a gastrointestinal emergency requiring prompt management to avoid fatal outcome. Although a majority of patients respond to conservative treatment, those not responding have been treated with intravenous cyclosporine or emergency surgery. Infliximab has been tried in patients with severe steroid-refractory ulcerative colitis. We report the successful use of this drug in the management of toxic megacolon in a 48-year-old woman not responding to the routine measures and who refused surgery.
|Original language||English (US)|
|Number of pages||2|
|Journal||Indian Journal of Gastroenterology|
|State||Published - Jan 1 2004|
- Inflammatory bowel disease
- Ulcerative colitis
ASJC Scopus subject areas