Infliximab in the treatment of ulcerative colitis with toxic megacolon

Sreeram Parupudi, K. S Pavan Reddy, Guduru V. Rao, Darisetty Santosh, Duvvuru Nageshwar Reddy

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Toxic megacolon is a gastrointestinal emergency requiring prompt management to avoid fatal outcome. Although a majority of patients respond to conservative treatment, those not responding have been treated with intravenous cyclosporine or emergency surgery. Infliximab has been tried in patients with severe steroid-refractory ulcerative colitis. We report the successful use of this drug in the management of toxic megacolon in a 48-year-old woman not responding to the routine measures and who refused surgery.

Original languageEnglish (US)
Pages (from-to)22-23
Number of pages2
JournalIndian Journal of Gastroenterology
Volume23
Issue number1
StatePublished - Jan 2004
Externally publishedYes

Fingerprint

Toxic Megacolon
Ulcerative Colitis
Emergencies
Fatal Outcome
Cyclosporine
Steroids
Therapeutics
Pharmaceutical Preparations
Infliximab

Keywords

  • Inflammatory bowel disease
  • Ulcerative colitis

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Parupudi, S., Reddy, K. S. P., Rao, G. V., Santosh, D., & Reddy, D. N. (2004). Infliximab in the treatment of ulcerative colitis with toxic megacolon. Indian Journal of Gastroenterology, 23(1), 22-23.

Infliximab in the treatment of ulcerative colitis with toxic megacolon. / Parupudi, Sreeram; Reddy, K. S Pavan; Rao, Guduru V.; Santosh, Darisetty; Reddy, Duvvuru Nageshwar.

In: Indian Journal of Gastroenterology, Vol. 23, No. 1, 01.2004, p. 22-23.

Research output: Contribution to journalArticle

Parupudi, S, Reddy, KSP, Rao, GV, Santosh, D & Reddy, DN 2004, 'Infliximab in the treatment of ulcerative colitis with toxic megacolon', Indian Journal of Gastroenterology, vol. 23, no. 1, pp. 22-23.
Parupudi, Sreeram ; Reddy, K. S Pavan ; Rao, Guduru V. ; Santosh, Darisetty ; Reddy, Duvvuru Nageshwar. / Infliximab in the treatment of ulcerative colitis with toxic megacolon. In: Indian Journal of Gastroenterology. 2004 ; Vol. 23, No. 1. pp. 22-23.
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