Influence of burn size on the incidence of contamination of burn wounds by fecal organisms

R. Y D Fleming, S. T. Zeigler, M. A. Walton, David Herndon, J. P. Heggers

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Ischemia and reperfusion injury of the gut mucosa after severe injury have been shown to allow endogenous gastrointestinal tract microorganisms to pass into systemic areas (bacterial translocation); this has been hypothesized as a source of burn-wound contamination. To study this phenomenon, 53 pediatric patients with burns underwent routine fecal culture at the time of admission. These cultures were compared with wound cultures that were obtained at the time of admission and throughout their hospitalization. Patients were grouped according to burn size: Small (1% to 20% total body surface area burned), Moderate (21% to 50%), and Severe (>50%). The incidence of corresponding isolates was determined for each group and compared by analysis of variance. No difference in the frequency of corresponding isolates could be demonstrated between the Small (4.0%) and Moderate (7.7%) groups, whereas the Severe group (53.3%) demonstrated a significantly larger incidence of corresponding isolates (p < 0.0001). Translocation of gut flora after severe burn injury may account for some instances of burn-wound contamination.

Original languageEnglish (US)
Pages (from-to)510-515
Number of pages6
JournalJournal of Burn Care and Rehabilitation
Volume12
Issue number6
StatePublished - 1991

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Burns
Incidence
Wounds and Injuries
Bacterial Translocation
Body Surface Area
Reperfusion Injury
Gastrointestinal Tract
Analysis of Variance
Mucous Membrane
Hospitalization
Pediatrics

ASJC Scopus subject areas

  • Emergency Medicine
  • Rehabilitation
  • Surgery
  • Nursing(all)
  • Health Professions(all)

Cite this

Fleming, R. Y. D., Zeigler, S. T., Walton, M. A., Herndon, D., & Heggers, J. P. (1991). Influence of burn size on the incidence of contamination of burn wounds by fecal organisms. Journal of Burn Care and Rehabilitation, 12(6), 510-515.

Influence of burn size on the incidence of contamination of burn wounds by fecal organisms. / Fleming, R. Y D; Zeigler, S. T.; Walton, M. A.; Herndon, David; Heggers, J. P.

In: Journal of Burn Care and Rehabilitation, Vol. 12, No. 6, 1991, p. 510-515.

Research output: Contribution to journalArticle

Fleming, RYD, Zeigler, ST, Walton, MA, Herndon, D & Heggers, JP 1991, 'Influence of burn size on the incidence of contamination of burn wounds by fecal organisms', Journal of Burn Care and Rehabilitation, vol. 12, no. 6, pp. 510-515.
Fleming, R. Y D ; Zeigler, S. T. ; Walton, M. A. ; Herndon, David ; Heggers, J. P. / Influence of burn size on the incidence of contamination of burn wounds by fecal organisms. In: Journal of Burn Care and Rehabilitation. 1991 ; Vol. 12, No. 6. pp. 510-515.
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