Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses

Priya Luthra, Jacinth Naidoo, Colette A. Pietzsch, Sampriti De, Sudip Khadka, Manu Anantpadma, Caroline G. Williams, Megan R. Edwards, Robert A. Davey, Alexander Bukreyev, Joseph M. Ready, Christopher F. Basler

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66 Scopus citations

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Medicine and Dentistry

Biochemistry, Genetics and Molecular Biology

Immunology and Microbiology

Pharmacology, Toxicology and Pharmaceutical Science