Initial sequence characterization of the rhabdoviruses of squamate reptiles, including a novel rhabdovirus from a caiman lizard (Dracaena guianensis)

James F.X. Wellehan, Allan P. Pessier, Linda L. Archer, April L. Childress, Elliott R. Jacobson, Robert B. Tesh

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Rhabdoviruses infect a variety of hosts, including non-avian reptiles. Consensus PCR techniques were used to obtain partial RNA-dependent RNA polymerase gene sequence from five rhabdoviruses of South American lizards; Marco, Chaco, Timbo, Sena Madureira, and a rhabdovirus from a caiman lizard (Dracaena guianensis). The caiman lizard rhabdovirus formed inclusions in erythrocytes, which may be a route for infecting hematophagous insects. This is the first information on behavior of a rhabdovirus in squamates. We also obtained sequence from two rhabdoviruses of Australian lizards, confirming previous Charleville virus sequence and finding that, unlike a previous sequence report but in agreement with serologic reports, Almpiwar virus is clearly distinct from Charleville virus. Bayesian and maximum likelihood phylogenetic analysis revealed that most known rhabdoviruses of squamates cluster in the Almpiwar subgroup. The exception is Marco virus, which is found in the Hart Park group.

Original languageEnglish (US)
Pages (from-to)274-279
Number of pages6
JournalVeterinary Microbiology
Volume158
Issue number3-4
DOIs
StatePublished - Aug 17 2012

Keywords

  • Chaco virus
  • Dracaena guianensis
  • Marco virus
  • Phylogeny
  • Rhabdoviridae
  • Sena Madureira virus
  • Timbo virus

ASJC Scopus subject areas

  • Microbiology
  • veterinary(all)

Fingerprint Dive into the research topics of 'Initial sequence characterization of the rhabdoviruses of squamate reptiles, including a novel rhabdovirus from a caiman lizard (Dracaena guianensis)'. Together they form a unique fingerprint.

Cite this