Insect-specific viruses and their potential impact on arbovirus transmission

Nikos Vasilakis, Robert B. Tesh

Research output: Contribution to journalReview articlepeer-review

92 Scopus citations


Arthropod-borne viruses (arboviruses) are the causative agents of significant morbidity and mortality among humans and animals globally. In the past few years, the widespread adoption of next generation sequencing and metagenomics has led to a new era of virus discovery, where many novel viruses have been documented, exhibiting a restricted host-range in mosquitoes. They represent a wide-range of insect-specific viruses within the families of Bunyaviridae, Flaviviridae, Mesoniviridae, Reoviridae, Rhabdoviridae, Togaviridae, and the newly recognized taxon of Negeviruses. Collectively, their discovery has opened new vistas about the extent of viral diversity and evolution, their influence on vector competence and ability of their insect hosts to transmit human pathogens (e.g. arboviruses), and their potential development as biological control agents or novel vaccine platforms.

Original languageEnglish (US)
Pages (from-to)69-74
Number of pages6
JournalCurrent Opinion in Virology
StatePublished - Dec 1 2015

ASJC Scopus subject areas

  • Virology


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