Insulin-like Growth Factor-I et denutrition aigue ou chronique

Translated title of the contribution: Insulin-like Growth Factor-I in acute and chronic malnutrition

Steven Wolf, R. J. Ramirez, David Herndon

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Malnutrition is a common problem affecting many patients with both acute and chronic illnesses. Nutrient delivery via parenteral or enteral routes has alleviated some of the problems that arise from well defined nutritional deficiencies. However, it has made a much smaller impact on wasting associated with illness. Modulation of metabolism with exogenous agents is attractive as a means to improve outcomes in patients that are susceptible to wasting. Insulin-like Growth Factor-I (IGF-I) and Growth Hormone (GH) are hormones that can be used for this purpose, and may have widespread clinical utility to improve wound healing, maintain lean body mass, and preserve organ function. Studies are ongoing to elucidate the possible benefits of these agents.

Original languageFrench
Pages (from-to)275-288
Number of pages14
JournalNutrition Clinique et Metabolisme
Volume10
Issue number4
DOIs
StatePublished - 1996

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Keywords

  • AIDS
  • burn
  • IGF-I
  • IGFBP
  • malnutrition
  • postoperative care
  • renal failure
  • trauma

ASJC Scopus subject areas

  • Gastroenterology
  • Nutrition and Dietetics
  • Endocrinology, Diabetes and Metabolism

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